do I have to change Lupron? - Advanced Prostate...

Advanced Prostate Cancer

22,371 members28,137 posts

do I have to change Lupron?

LastMohikan profile image
15 Replies

tomorrow I will have 3.Lucrin injection and have appointment with MO. T value is high compared with last April data. So I think myself that Lupron has lost effect, perhaps I need to add Casodex to Lucrin or change it to Zoladex or other or keep continue with Lucrin . In the below table I tried share some data . I need your experience .

thanks...Umit

Written by
LastMohikan profile image
LastMohikan
To view profiles and participate in discussions please or .
Read more about...
15 Replies
Magnus1964 profile image
Magnus1964

Milk Lupron for all it's worth, then move on to casodex.

LastMohikan profile image
LastMohikan in reply toMagnus1964

thanks, you mean I need to get 3.injection than add Casodex (Lupron+Casodex)?

Magnus1964 profile image
Magnus1964 in reply toLastMohikan

Do not go on casodex until lupron stops working. I am a big believer in using drug one at a time. When one fails go to the next.

I would get the next shot and check the Testosterone again. If it's down around 20 or less, I'd check it again in a month. If it doesn't come down now or goes back up again, I'd try amother LHRH drug, possibly Firmagon (Degarelix) which is an LHRH antagonist.

Tall_Allen profile image
Tall_Allen

Did you have a 3-month shot in April? If so, it appears you waited too long.

LastMohikan profile image
LastMohikan in reply toTall_Allen

Dear Tall_Allen, I got it at 29April. I had to get next one at 29July, unfortunatelly I had 3.covid shot therefore I wait around 2 weeks . Otherwise all my blood treatment lab result could be effected. I mean I am just 12 days delay.

Tall_Allen profile image
Tall_Allen in reply toLastMohikan

12 days is a lot. It's effects can wear off quickly.

dac500 profile image
dac500 in reply toTall_Allen

Sometime testosterone takes much longer to recover. Last time I went on break my testosterone was still at castration level (< 20) six months after last 3 month Lupron shot.

LastMohikan profile image
LastMohikan in reply toTall_Allen

MO changed Lucrin to Eligard , yesterday I got shot. we will check 1.5months later PSA and Total T. If T is still high than he will change the treatment

podsart profile image
podsart in reply toLastMohikan

3 covid shot— 2 regular and a booster? Which covid Pfizer, moderna …?

LastMohikan profile image
LastMohikan in reply topodsart

2 sinovac (Chines), last one pfizer

podsart profile image
podsart in reply toLastMohikan

Interesting, know some were trying for booster before cdc acts, so u could mix vaccine manufacturers, wasn’t sure about that

Good luck

London441 profile image
London441

Yes sometimes it recovers slowly. And sometimes quickly!

Sure get your shots on time for a bit. But if I do that and then blow another 215, that’s when I say it’s already stopped working.

MateoBeach profile image
MateoBeach

Yes, the Lucrin is wearing off too fast and T recovering too high in just 4 months. Either need to spa e closer, 3 months or less and recheck, or switch to longer lasting alternative. Three month or six month Eligard or Lupron tend to wear off very slowly. COVID booster is another topic. If it’s been close to six months then immunity likely waning and insufficient for Delta variant. I know, I just recovered from a terrible case of it.

LastMohikan profile image
LastMohikan in reply toMateoBeach

thanks dear MateoBeach. Mo changed it to Eligard 3 monthly shot, than we will wait the next test result to decide to what to do. perhaps it will replaced by Zalodex or other combined treatment..thanks...Umit

Not what you're looking for?

You may also like...

Need advice if I should do Docetaxel/Lucrin even when PSA continues to drop to 0.41

Latest PSA has come down from 1.35 in April to 0.41 in July. I have multi mets on my backbone and...
bellyhappy profile image

lucrin injections v firmagon

Hi Anyone experienced having Lucrin injections .I have been self injected firmagon since march...
Brianne07 profile image

Results after 5th Docetaxel infusion and just started 6th

The PSA had dropped from 0.217 to 0.164. This is good news. I was diagnosed on Nov2019 with PCa...

Enzalutamide or Darolutamide

Hi, I have advanced metastatic hormone sensitive prostate cancer and as well as my usual three...
x-rays1 profile image

Now on ADT, what to add?

I found out in October last year that I had several tumours in my spine, one in my rib and some in...
x-rays1 profile image

Moderation team

Bethishere profile image
BethishereAdministrator
Number6 profile image
Number6Administrator
Darryl profile image
DarrylPartner

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.