Has any one had success with salvage radiation for recurrence of cancer

[Channelhomec]

Gleason >7 3+4 should you use utrasesative psa test or regular test

[Emak1]

I was G7 (3+4). Initially had surgery, 18 months later BCR, started at 0.17 and moved to 0.29 within 3 months. Went on ADT for 7 months (Firmagon) and had 40 radiation treatments.

Coming up on 3 yrs this June, PSA every 6 months, so far so good, undetectable PSA. Long term who knows, but as of today it is good

[Channelhomec in reply to Emak1]

Thanks for the information

[Channelhomec in reply to Channelhomec]

And good luck

[pjoshea13]

I was a Gleason 4+3 17 years ago. My post-RP PSA was 0.3 & I opted for salvage radiation [SR]. PSA dropped from 0.8 back to 0.3, but rose again to 0.8 three months later. Back to square one. What did it achieve?

Of course, SR monotherapy is not performed with curative intent. It's aggressive & buys time for some. Overall, I think it worthwhile when one has Gleason Number 4 cells. Of course, after 17 years it is tempting to look back at all decisions as having been correct.

Here's an old Johns Hopkins study on SR statistics: [1],

-Patrick

[1] ncbi.nlm.nih.gov/pmc/articl...

[Channelhomec in reply to pjoshea13]

Thanks for the information

[Magnus1964]

Yes, I had salvage radiation toy ischemia. It was successful, I have not had any problems for 7 years

[Channelhomec in reply to Magnus1964]

Thank you for the information

[dentaltwin in reply to Magnus1964]

"toy ischemia"?

[Magnus1964 in reply to dentaltwin]

I meant to say ischium, the large bone in the posterior from the hip.

[dentaltwin in reply to Magnus1964]

Thanks-- I probably should have been able to figure that out for myself.

[Tall_Allen]

I know several men who have. After the salvage radiation there is no longer any need for an ultrasensitive PSA test. There is nothing you would do differently if your PSA is 0.05 or 0.1.

[Channelhomec in reply to Tall_Allen]

Thank you

[RCOG2000 in reply to Tall_Allen]

Ultra sensitive Could be of use if one is tracking psa doubling time

[Tall_Allen in reply to RCOG2000]

No, it isn't. PSA doubling time is only defined for values above 0.1. It is meaningless for lower values.

[donits]

My history:2002, Gleason 6 (3+3) PSA level below 10, and LDR Brachytherapy.

2006 biochemical recurrence and salvage radiotherapy 45Gy to the lymph nodes of the abdominal cavity only, and Casodex 150mg x 1 approx. 3 years, PSA level 0,6 all the time until 2018 where it increases to about 2.xx. Imaging tests (PSMA 68Gall + scintigraphy) showed nothing ??? Then again Bicalutamide 150 x 1 (and Atorvastatin 80mg x 1 clinical trial) + some dietary supplements. PSA level currently below zero (fluctuating).

[Channelhomec in reply to donits]

Sounds like your doing well god bless thank you

[Steve507]

3 months ago finished Salvage Radiation with one Zoladex injection in November. Been <0.01 Since January. I was only 0.05 but went proactive. Leaving Doha for good in July wo health insurance but got a Robotic Rad Prostatectomy and Salvage Radio for free.

[Channelhomec in reply to Steve507]

Looks like you made the right decision good luck had o.o6 for six years till it started to moved up 0.14 then salvage

[Steve507 in reply to Channelhomec]

Were you ever 0.01? How long after RP did you get to 0.06?

[Channelhomec in reply to Steve507]

Never @0.01 right after surgery ultrasesative psa 0.06 for 5yrs my uroligest just keept an eye on it said it was still undertected at that number. >gleason >had3>4, with small positive margin at apical sight