I haven’t been posting much due to school and things have been relatively okay. My dad had a PSA test 3 months ago where it showed a PSA of 0.07. His PSA has been hurdling around 0.07 for a couple of months. My dad had his regular PSA check up today after 3 months and it spiked up to 0.11. He is on zytiga (he has been on zytiga since 2019) and getting hormonal therapy shots. His doctor said they will check his PSA again 3 months later and if there is another rise in PSA, then they will do a bone/CT scan and will possibly have to change treatment. I’m wondering what should the next treatment be in the event that his PSA rises? I know standard of care would be to move onto chemo, but is there anything else we can try?
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chocolatelover_123
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My dad has switched from prednisone to dexamethasone within his zytiga journey
I wouldn't jump to conclusions. A PSA rise of 0.04 could be a result of lab error, time of day, what your father ate, etc. If he does get scans and they are clean then Zytiga is still effective. Try and squeeze every day possible out of Zytiga. It's the scans not the PSA.
Hi there,I am in a similar position with slowly increasing PSA. After chemo, I was undetectable, then it went to 0.12, then 0.16 and recently 0.19. My onco was not particularly bothered by this (although I was). He said PSA can fluctuate up and down when at low levels and that the measure they use is to look at the time it takes for your PSA to double. My GP told me that he wouldn't worry too much about rising PSA until it gets to 10.
It wouldn't hurt to ask your onco what he thinks sbout it though.
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