Diet for PCa

[Garp41]

townsendletter.com/article/...

Good article.....Doug

[Tall_Allen]

Poor understanding of research, imo. It's always a mistake to put faith in retrospective observational data.

[drmoose]

Not sure of the studies and logic (fully agree with TA on dangers of historical pattern matching), but the author's "bottom line" advise seems reasonable:

No smoking;

If BMI is 27 or higher, lose weight;

Exercise rigorously, do something to sweat;

Eat lots of vegetables (particularly tomato sauce and cruciferous vegetables);

Eat more vegetable fats (i.e. fish, nuts, vegetable oils, soybeans, avocados, and flaxseed) and fewer saturated fats. Eat less carbohydrates;

Drink coffee – regular or decaf doesn’t seem to matter;

Limit eggs and poultry with skin on;

Limit whole milk if your BMI is high, probably should even if it isn’t; and

Limit refined grains, sugars, processed meat, and high-fat dairy

There are a few subtle points that one could argue (decaf coffee may not be as good as full coffee , I would avoid "cheap" vegetable oils and stick to high quality olive or nut or avocado oils) but following this advice should not hurt, and may help overall. One can certainly choose to follow much stricter guidelines if you are into that.

I personally would do this as a mitigation for whatever therapeutic choses I make in the future, i.e. certainly hope it would help with response and progression, or at least with side-effect management.

[dhccpa]

Thanks I do all that since 7/2019. Jibes generally with Mayo and PCF dietary guidelines.

Regarding Vitamin E, some say tocotrienols should be studied more, whereas most studies have used tocepherols, as mentioned in the articles.

Diet is difficult to study and verify, as is smoking or other types of consumption. But the findings in this article seem to be gaining ground quickly.

[ocman]

I try and limit eggs, but need to do better.

[jeff1257]

Since the choline in eggs is in the yolks, what about eating egg whites. I’d think egg whites would be ok.

[Garp41 in reply to jeff1257]

Not IMO.......egg whites haves a lot of leucine......cancer promoter.

Doug

[j-o-h-n]

Shells only.......

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 11/16/2020 10:03 AM EST

[monte1111]

I just bought eggs - I'm going to eat them. Fish stink - literally - I pass. Sweat? The only time I sweat is when a cop is right on my bumper.

[timotur]

Doug: thanks for posting, very good read, and corroborates the studies I've read on the risks of milk and dairy (eggs) in PCa progression.

Milk: the bad guy is casein-- "PC3 cells treated with 1 mg/mL of α-casein and casein showed increased proliferation (228% and 166%, respectively), and the proliferation of LNCaP cells was also enhanced by 134% and 142%, respectively. "

ncbi.nlm.nih.gov/pmc/articl...

Eggs: the bad guy is choine-- "A plausible mechanism that may explain our observed association between eggs and prostate cancer progression is high dietary choline. Egg consumption is a determinant of plasma choline, and higher plasma choline was recently reported to be associated with a greater risk of prostate cancer (50, 51). Malignant prostate cells have higher choline concentrations than do healthy cells, and choline kinase is overexpressed in prostate cancer (52–54). In addition, because of the increased uptake of choline by progressing prostate tumors, radiolabeled choline is used to identify early prostate cancer recurrence (55). No studies have examined dietary choline and prostate cancer risk or progression; however, higher dietary choline has been associated with an increased risk of colorectal adenoma in women (56).

academic.oup.com/ajcn/artic...

Since diagnosis, I've cut back milk to one quart/week and 3 eggs/week from one gallon/wk and eggs everyday.