Decreasing testosterone level - Advanced Prostate...

Advanced Prostate Cancer

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Decreasing testosterone level

Prellch profile image
12 Replies

After chemo and radiation treatment for Gleason score of 9, 7 years ago for PC, my testosterone has since always been around 90-100, but recently it has dropped to 53. Any thoughts on how I can safely raise my testosterone level, or why it has dropped.

Thanks for your help.

Chuck

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Prellch
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12 Replies
Tall_Allen profile image
Tall_Allen

My T levels dropped immediately after radiation, but recovered after a couple of years. But over the years it steadily dropped again due to aging. I now use TRT. As long as your PSA is below 0.5 and has been that way for a while, you should be able to get TRT to maintain normal T levels:

prostatecancer.news/2020/06...

Prellch profile image
Prellch in reply to Tall_Allen

Thanks for help.

Chuck

honolu profile image
honolu

I have no experience with radiotherapy, still doing the holistic & integrative strategy. I don't want chemo but may entertain proton radiation treatment. psa is 23 going to lab every 6 months.

pjoshea13 profile image
pjoshea13

The quick fix is a testosterone [T] patch or T-cypionate self-injection (much cheaper). I have known 2 guys with T as low as yours. They were given Cipro [Ciprofloxacin] to no avail & ended-up on T replacement.

Obviously, you would monitor your PSA.

-Patrick

Prellch profile image
Prellch in reply to pjoshea13

Thanks for your help.

Chuck

Prellch profile image
Prellch

Thank you all very much for your feedback.

Chuck

Prellch profile image
Prellch

Thank you for your rely.

Chuck

billd50 profile image
billd50

I was also treated with Radiation and Chemo 5 years ago for Gleason 9s and a 10. But I also had 2 years of Lupron. My T was close to 0 during Lupron but returned to around 300 after

about 15 months. Were you on Lupron or Firmagon? Do you know what your T level was before all the treatments? I understand that once you pass the 3 year point with ADT, the

recovery of T to pre treatment levels is more difficult. You should definitely confer with an Oncology doc.

NecessarilySo profile image
NecessarilySo

Since Testosterone feeds prostate cancer cell growth, I would think you would want to keep it down. I mean that is the whole point of hormone therapy, keeping T low. Right?

j-o-h-n profile image
j-o-h-n in reply to NecessarilySo

That's exactly what I thought which is as far as I'm concerned NecessarilySo...

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 11/09/2020 6:35 PM EST

MateoBeach profile image
MateoBeach

If your PSA is low and stable (<1.0) you can probably do a personal trial of TRT and monitor response. Must be stopped if PSA takes off. But no progression is seen in patients for whom this happens and PSA comes back down for most. However this is from several small trials in different stages of PC. No definitive randomized trials yet. So most docs are not comfortable with it and will not prescribe it for a personal trial. There are exceptions though and some here doing well on high doses of T. Or some form of BAT. Search other posts on this topic for discussion and links to current research. Or PM me and I can send several to you.

Prellch profile image
Prellch

Thanks for your helpful response.

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