C-11 Choline Pet Scan

[Sun1115]

I live in Florida . Does anyone know if Mayo Clinic in Jacksonville,Fl have the C-11 Choline Pet Scan like Mayo , Rochester?

[Tall_Allen]

It's outdated, if you can get an Axumin PET scan.

[Sun1115 in reply to Tall_Allen]

Thanks for your reply . . Which scan is more accurate? Dr Kwon uses the C-11 Choline , but that’s a trek for me , all the way up to Rochester MN . Especially with no snowshoes.

[Tall_Allen in reply to Sun1115]

Axumin - definitely.

[addicted2cycling in reply to Tall_Allen]

Just had F18 Axumin (totally clear results) yesterday with PSA @ .6 and thinking that if another increase in next test will ask about GA-68 PSMA and also will ask where the 18F DCFPyL PET is available for better recognition than F18.

[Tall_Allen in reply to addicted2cycling]

Why are you pursuing those scans?

[addicted2cycling in reply to Tall_Allen]

Started off with GL10 in 2015. Treatment done but had PSA rise in 2018 and Axumin found recurring spots so treated. Recently had PSA ,2 to .4 in 3 months then 1 month later .6 so yesterday's Axumin that did not have uptake and thinking some none sensitive F18 might be hiding out so if another PSA increase maybe a GA68 PSMA for different recognition of possible mets

[Tall_Allen in reply to addicted2cycling]

Congratulations on the clear scan! Are you taking Lupron and Zytiga?

[addicted2cycling in reply to Tall_Allen]

No. I'm the 2015 GL10 having had castration + Cryo + immuno (unproven experimental 3 drug cocktail) injection + Cypionate bi-weekly - all allowing bicycle rides like 130 miles on Sunday and rockin till I drop. Just thinking from research that GA68 PSMA might result in an uptake that the PCA doesn't respond with using F18.

[Tall_Allen in reply to addicted2cycling]

I'm not sure what you mean by F18 - NaF18? DCFPyL?

pcnrv.blogspot.com/2016/12/...

So, do you want a more sensitive scan to go after metachronous metastases? While that may or may not prove to be beneficial (jury's still out), we know it is beneficial to add Zytiga, Xtandi, or Erleada to your orchiectomy.

[addicted2cycling in reply to Tall_Allen]

Willing to not wanting to add anything until shown by scans. Adding those mentioned would undoubtedly impact this soon to be 70yo's 2 to 3 times per week 100+ mile bicycle rides, current QOL and possible thickness of wallet. :0)

[addicted2cycling in reply to Tall_Allen]

Not as well educated all things PCa scanning like so many here, my take is that Axumin IS NOT a PSMA sensitive scan like GA 68

Yet -- 18F-DCFPyL-PET/CT, is a prostate-specific membrane antigen (PSMA) targeted PET agent

[Tall_Allen in reply to addicted2cycling]

No Axumin is not a PSMA-based scan. I don't understand your point?

[addicted2cycling in reply to Tall_Allen]

My thinking(can very well be 100% incorrect) is that the Ax uptake will not identify when a PSMA scan will so even though the Ax did not find anything, something could still be there causing a PSA rise that a PSMA scan would show and from some internet searching it appears that the 18F-DCFPyL, not the 18F-fluciclovine (AXUMIN), is more sensitive than a GA68.

[Tall_Allen in reply to addicted2cycling]

I thought I gave you this link - did you read it?

pcnrv.blogspot.com/2016/12/...

[addicted2cycling in reply to Tall_Allen]

Sorry, neglected to look and guess my confusion (DUH) is in the list having #1 as shown F18-DC..... and recent internet searching I found it as 18F-DCFPyL not as listed F18-DCFPyl with F18 being the Axumin

F18-DCFPyL

F18-DCFBC

Ga68-PSMA-HBED-CC (Ga68-PSMA-11)

Fluciclovine (F18 - FACBC)/ Axumin

C11-Choline/ C-11-Acetate

F18-Choline

NaF18

F18-FDG

Once again, still a neophyte here.....(DUH x 2)

THANKS

[Tall_Allen in reply to addicted2cycling]

F18 - Fluorine -18 is just an atom that emits positrons (like Gallium 68 or Carbon 11) - it is the molecule that it is attached to (the ligand) and how it is attached that is important.

[Litlerny]

Jax Mayo uses the Axumin PET scan. According to my Jax Mayo oncologist, Dr. Tan, it is just as accurate as the C-11 scan used in Rochester. I’ve had the Axumin scan at the Jax Mayo.

[Sun1115 in reply to Litlerny]

I have PC in pelvic lymphnodes and have been on Lupron ( 3 month injections) for three years . And it has worked good . It has kept my PSA undetectable for about three years . However, recently PSA has gradually started to increase. The last nine months resulted in 0.23 , .366 , and recently 0.631 . I am somewhat concerned. Is it possible I need a change of treatment? Should I look into a Auximin scan or any other scan to determine if cancer is coming back ? Is it too early for me to worry? I thank you for your input .

[addicted2cycling in reply to Sun1115]

Just saying that my Axumin PET yesterday was ordered by my treating doctor with a PSA of 0.618 up from 0.449 in 1 month's gap.

[Sun1115 in reply to addicted2cycling]

That’s interesting. It tells me the doctor isn’t taking any chances . What’s your input on this Tall Allen ?