Prostate cancer

[Mrsram]

Hello everyone wanted to share that my father continues to show progress . His PSA levels are at 0.9.His doctor stated he wants him at 0.1. He also shared that a new medications has just been approved has anyone heard about it?

[AZjame]

New medication is Nubeqa (darolutamide):

"A prescription medicine used to treat men with prostate cancer that has not spread to other parts of the body and no longer responds to a medical or surgical treatment that lowers testosterone, such as androgen deprivation therapy (ADT)."

[Tall_Allen]

Several new meds have recently been approved for different situations. I assume he is metastatic and hormone sensitive - right? In that case, the newest medication approved for that is Erleada. Other medications previously approved for that are Zytiga and Taxotere. You can read about treatments for men in this situation here:

pcnrv.blogspot.com/2017/06/...

[Mrsram in reply to Tall_Allen]

Thanks

[podsart in reply to Tall_Allen]

I thought I read that daralutamide has some ability re dealing with AR mutations while apalutamide doesn’t . Assuming he has a choice , would daralutamide be more attractive?

[Tall_Allen in reply to podsart]

If he is mHSPC, his only choices are Zytiga, Erleada, and Docetaxel. Xtandi will probably be approved soon. Nubiqa is only approved for non-metastatic CRPC.

[podsart in reply to Tall_Allen]

Thanks

Say, each were available regardless of condition, which would you choose?

[Tall_Allen in reply to podsart]

Whichever my insurance would pay for. There have been no comparative studies.

[podsart in reply to Tall_Allen]

Thanks