Psa under and down over the years

[Deemond1]

Psa was 9.8 it was been going up and down last 5.8 2012 had pre cancer cell now going for mir scan is a good or bad psa going up and down

[BarronS]

PSA fluctuation can happen for many of reasons. The only way to find out if it's bad is after the scan. If the scan does not satisfy you, ask for a biopsy of the prostate. You don't want to sit on it and let it metastasize if you do have a high grade cancer. They did this with my father.

Did a biopsy of only 2 cores. Found that it was a gleason of 7. Told him with his PSA and gleason score to "not worry. It's low grade and won't spread quick". Let him go 8 months before surgery and then it metastasized.

[Tall_Allen]

Do you have advanced prostate cancer? What treatments have you had?

[Deemond1 in reply to Tall_Allen]

No I do not no if I have cancer yet I have been doing psa test for years first mri scan

[Tall_Allen in reply to Deemond1]

I asked because this is a forum for men with advanced prostate cancer. Fluctuating PSAs before diagnosis usually indicate prostatitis.

[Deemond1 in reply to Tall_Allen]

Sorry tall Allen I post on this site

[Tall_Allen in reply to Deemond1]

No problem - you might get more appropriate responses on Darryl's other site:

healthunlocked.com/prostate...

[bassguy]

Hi Deemond. Sort of similar frustrating experience here. 55yo.

PSA fluctuating over the past few years. Beginning in 2017-

2.1 2017

1.5 2018

4.6 2019 Feb. ( intermittent re-checking began due to big jump)

3.8 2019 Mar & 4Kscore 7%

2.2 2019 Apr

5.9 2019 June

4.2 2019 June again

All DREs normal

June had 3T mpMRI. Results showed nothing (except some disc degeneration) with a PiRads score of 1 (highly unlikely that there is the presence of high grade cancer) Apparently these MRIs have a negative predictive value of close to 90%, although the radiologist thinks even higher!

I understand your frustration...and your worry, if you have any. My urologist was quite encouraged, but I too never showed any signs of infections in my urines. He's thinking BPH (as was the doctor who interpreted my MRI - "uniform shape, large volume").

I am waiting a few months for a re-test PSA. Probably September or October.

Think about an MRI. My insurance paid for both - the 4K and the MRI. My urologist had to advocate big time for the MRI. They denied it the 1st time but he was able to argue/persuade at his second attempt. He is conservative inasmuch as NOT wanting to biopsy blindly and at this point he thinks it's counter-indicated to do so.

Good luck.

[Deemond1 in reply to bassguy]

bassguy thank you for your reply I am down for mri scan soon but it has been worrying may be waiting few months still

[j-o-h-n]

Tell us more about yourself. Please.

Happy Birthday Uncle Sam.

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 07/04/2019 7:31 PM DST