LDN and Cancer

[gsheltonone]

Has anybody heard of "LDN"

MY "OD" told me, LDN has been shown to increase your Immune System and help to attack some forms of cancer.

LDN is short for Low Dose Naltrexone. Naltrexone is a drug that was approved by the FDA in 1985 to treat opiate dependencies. It is marketed under the trade names ‘Revia®’ and ‘Depade®’ and in some countries (including the United States), an extended-release formulation is available as ‘Vivitrol®’.

What is Low Dose Naltrexone (LDN)? | LDNscience

ldnscience.org

According to a report in The International Journal of Oncology, giving low dose naltrexone (LDN) to cancer patients can improve the immune system’s ability to kill cancerous cells, as well as improve the efficacy of standard cancer treatments and immunotherapy.

Candyman

[pjoshea13]

I joined the LDN group some years back, but withdrew after a few months.

See:

lowdosenaltrexone.org

-Patrick

[snoraste in reply to pjoshea13]

Patrick - can you expand on this please.

[pjoshea13 in reply to snoraste]

I didn't see signs that it had been useful to men with PCa, but that was some years ago.

I can't comment on its effectiveness for other forms of cancer.

I have no negative feelings about the group. Those who are interested should join the group & ask men with PCa for their experiences. I would look for men with advanced PCa who had been using LDN for ~12 months. + other forms of treatment.

-Patrick

[TFBUNDY in reply to pjoshea13]

Hi Patrick. You are the repository and guru for medical and pharmacological control of this horror. My LDN experience... DX PSA 4.8 gleeson 3+ 4. PSA rose to 6.4 over 3 months then dropped to 5.1 following panic dieting. Sought out LDN. About 2 months later, after 2 weeks of LDN PSA rose to 8.1 causing panic in the camp. Carried on with LDN and added hymecromone. 6 weeks later PSA was 4 4, just before focal HIFU, last PSA 1.2. I still take it, but hard to get. About $50 for one pack - lasts a year - sourced from Cambodia (Revia)

[pjoshea13 in reply to TFBUNDY]

Thanks for the feedback! -Patrick

[HOPEFULSPOUSE]

My husband was on LDN for a bit over a year when he was first diagnosed in 2013. He was also on zoladex at that time and a monthly bisphosphonate IV. Hard to know what the exact criteria would be for establishing effectiveness against PCa. He never got sick during that time (i.e. no winter colds or flus, etc.) His PSA went down from 779 to less than 2 in that first year (he was only on the zoladex for about 6 months before stopping it). When he stopped, the PSA was around 30 and over the next 6 months with natural supplements only (+ the bisphosphonate) it went down to 1.33.

He stopped because over the course of that first year he was taking so many natural supplements and decided that he needed to streamline his regimen.

[FCoffey]

I took it for several years. The only consistent effect I noticed is that it gives you quite vivid dreams. I can't say what it did for my prostate cancer, I have the n=1 problem.

Three of my team of doctors strongly recommended it. When they agree like that, I've learned to listen.

I stopped in October while trying some other treatments. I may start again in a month or so. It certainly did not hurt anything but my wallet, and it may have helped.

Good luck to you.

[Arthur479]

I have been on it for a couple years. No issues, other than vivid dreams. Hard to tell if it is working as I am doing many other things.

[CrocodileShoes]

I took it, and I have to say I felt great on it. I'm amazed to hear teams of doctors supporting it - some UK general practitioners have been threatened with removal of licenses for prescribing it. I took it when I was diagnosed with colon cancer (stage 1) I stopped after I had surgery, and haven't returned to it (it's difficult to get hold of here in the UK) since PCa recurrence. Like Patrick, I couldn't find any evidence that it helped PCa. There's a feature-length documentary on it kicking around (try Googling LDN documentary)

I may well give it a try again...

[j-o-h-n]

Vivid dreams huh? Wet?

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 05/23/2019 4:31 PM DST

[tom67inMA in reply to j-o-h-n]

I can only dream of wet dreams these days. As for vivid dreams, I get enough of them without LDN. Last night, and I'm not making this up, I dreamed of a "potato chip repair kit" for those broken bits in the bottom of the bag. If that's not weird enough, it was part of a Doctor Who dream.

[whatsinaname in reply to tom67inMA]

Interesting "dreams", Tom !!!

[j-o-h-n in reply to tom67inMA]

That's weird, I dream of soldering broken pieces of pretzels.. I think you need a shrink.👀

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 10/09/2019 5:17 PM DST

[tom67inMA in reply to j-o-h-n]

That makes sense, much less likely to set the pretzels on fire compared to welding.

[j-o-h-n in reply to tom67inMA]

Cut out the running and just see a shrink....👀

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 10/09/2019 6:58 PM DST

[Kevinski65]

I took noscapine for awhile. It's gotta be ordered from Belgium. It's a cough syrup. I don't know if it did anything. I used it to wash down 4mu another European wonder.