"In the PSMA-PET group, PSMA-PET CT detected PC in 196/200 (98%) pts! 55% had local recurrence, 54% had pelvic nodes (N1), and 55% had any extrapelvic distant metastatic disease despite negative conventional imaging. Ultimately, 24% were diagnosed with local recurrence only, 29% with oligometastatic (1-3 lesions) and 46% with polymetastatic disease. "
This is not at all surprising, but it may be a mistake to get a PSMA-based PET scan for men with nmCRPC because insurance may not want to cover Erleada once mets have been detected, and there is no known benefit for met-directed therapy.
" Patients with isolated, painful bone lesions may be treated with palliative external beam radiation. Additionally, oligometastatic disease may be treated to slow progression."
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