The K Arm of the STAMPEDE TRIAL is looking at the effect on PSA, if any, of adding Metformin to ADT in non-diabetic PC men. I have seen a few posts on here from people who are taking part in that trial where the PSA seems to be coming / staying down, but I was wondering if there are a number of participants out there that could give us an idea informally, of how they are going with their PSA. The trial itself started in 2016 and won’t report until 2024, so any indications before then would be interesting to hear. If you respond can you give your pre-trial PSA, time on trial, and current PSA? Side effects would be of interest too. Thanks to any who respond.