Link between ovarian and prostate cancer - Advanced Prostate...

Advanced Prostate Cancer

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Link between ovarian and prostate cancer

MyDad76 profile image
7 Replies

A while ago I read an article (need to find the link) that if mother had ovarian cancer sons have increased risk of prostate cancer.

This was the case with my dad: his mom had ovarian cancer and both he and his brother prostate cancer. By the same analogy I have increased risk of ovarian cancer.

Just curious: anyone has similar family history? If so, did it affect treatment choices?

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MyDad76
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pjoshea13 profile image
pjoshea13

see: cancerdiscovery.aacrjournal... -Patrick

MichaelDD profile image
MichaelDD

My mother had breast cancer. I had stage 2 breast cancer in 2004. Had a radical mastectomy and 4 months of chemo. Plus 5 years of tamoxifen .

2016 I was diagnosed with Gleason 8 PSA 12 Stage 3 prostate cancer. Had DaVinci removal of prostate. Had persistence PSA/it never stopped. 38 radiation sessions 3 months later. Still fighting and trying to figure out the next moves??

2017 I have had genetic testing done and am fortunate to find that there is no gene being spread to my son , grandsons or granddaughters.

The folks at genetic testing time were interested in the combo breast cancer /prostate cancer. I didn't hear anything about the tie between ovarian and prostate. Who knows.? honestly I was shocked when I found out I have prostate cancer after having breast cancer. Good luck to you on your hunt and journey!!

Desanthony profile image
Desanthony

There is a genetic research facility attached to my cancer hospital and a couple of years ago they were looking into the link between ovarian cancer and prostate cancer. I have heard nothing since that time but I may ask now that you have reminded me about it. Although neither of my parents died of cancer it was thought that my Dad could have had pc but he was so unwell at age 88 we decided not to put him through all the tests and he died at 89 of other causes. My grandparents did have cancers and died relatively young by today's standards - but, as far as we know not ovarian or prostate cancer. My late wife had thyroid cancer at 40 and died of ovarian cancer at age 57, her brother died of pc at 67, her sister has also had thyroid cancer. If any link is found I would be interested as I am the father of two sons just in their 50's so have made them have PSA tests and urged them to be tested regularly.

MyDad76 profile image
MyDad76 in reply to Desanthony

My fathers brother had both PC (cured by surgery) and thyroid cancer. And as mentioned their mother had ovarian cancer. I will try to google and find the reasearch where I read about the (potential) link between the ovarian and prostate cancer.

Lynsi13 profile image
Lynsi13

Very interesting. My grandmother died from ovarian cancer and now my dad has PC. However, we did genetic testing and didn’t find any genetic data that would suggest a link.. however, genetics is still developing and a gene linking the two diseases may yet to be discovered!

MyDad76 profile image
MyDad76

Just wanted to share the links. I will try to get my dad tested - as mentioned above his mom had ovarian cancer and his brother who had surgery for prostate cancer around 20 years ago is now dying from metastatic prostate cancer.

"Notably, these HBOC mutations, especially BRCA2, are responsible for the majority of hereditary prostate cancers. “It’s important to know about BRCA2 because BRCA2-associated prostate cancers are some of the most aggressive,” "

health.clevelandclinic.org/...

medicine.duke.edu/medicinen...

Bspouse profile image
Bspouse

My husband has prostate cancer - his sister had ovarian cancer. I feel there is a link between the 2 since theses are both hormone based cancers. They both had genetic testing and both came up with no known gene mutations. But I think either they just haven't identified the right gene(s) for this yet, or maybe something in their environment growing up, Since we have 2 daughters , we would really like to know if they have a genetic risk for ovarian cancer.

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