Hi all. My father (76 years old) is on casodex monotherapy. This is quite common theraphy in our parts of the world - they use it untill it works, than they add Lupron. He Gleason is 7 (4+3, tumor present in 10% of tissue evaluated (it was discovered during TURP procedure, stage 2b) and has been on Casodex for over a year. I will also seek second opinion on the theraphy next week.
My question is: for those that have used casodex as monotheraphy or in combination, did you experience any voice changes? My fathers voice became weaker. He also has other typical side effects such as fatigue, loss of muscle strenght.
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MyDad76
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Casodex - yes, my voice cracked... I became very weak...lost a great deal of muscle...all that... I took it as neoadjuvant therapy (before surgery) to shrink a huge tumor.
Thank you for replying! I'm getting a second opinion next week. If my fathers cancer is still confined to prostate as it was when diagnosed I will ask for other treatment options like radiotheraphy or surgery. Casodex is quite difficult on my dad.
If he's healthy enough, surgery is the way to go... I had surgery in 2002 - was "clear" for 12 years, in an "indolent stage" for 3... didn't "fail" until this December....15 years I might not have had. RIght now, doing 40 radiation sessions, hoping for another break.
One more question if I may. Did they know you were stage 3 at time of diagnosis or was that only clear after surgery? If only after surgery, do you recall what was you stage and Gleason before it? Also did you have any joint and pack pain while on Casodex? Thanks! I will go for second opinion re my dad. Just interested how it was in your case.
Not at the time of surgery, exactly - I'll explain...I was Dx as a stage T2b after the biopsy, but advised the pathologic stage would most likely be higher if I had surgery -I was advised to have radiation only. My wife said, bullshit. So, we found a doctor willing to do the surgery -Robert Myers @ Mayo, now retired. It was then that I was a stage as a T3a. RE: Casodex...I had back and leg pain BEFORE I took Casodex, but while on it as neoadjuvant therapy this disappeared. HAven't had that trouble since - well, doing squats recently strained my low back, but rowing on the Concept 2 erg helped a ton. Oh! Gleason! Clinical was Gleason 3 + 4; pathology was 4+3.
A bit too long... 2 months - but, that was because the surgeon at Mayo specified I had to be under 230 pounds before surgery. I was about 265, hence, the wait and the Casodex.
Yes, my dad is otherwise healthy. No other diseases. I'm crossed at doctor to even have him on Casodex for so long. I hope radiation brings good results to you! I've heard/read of remissions for several years!
When a man is on hormone therapy with Casodex or the other common drugs there is usually a loss of muscle strength and stamina. The best treatment for that is exercise. It won't necessarily make him as strong as he was before treatment, but it can make a really big difference in his ability to handle the requirements of daily life.
The simplest exercise for this purpose is walking. He should start with whatever he can handle and build up, walking every day, with a goal of several miles a day. He can bring a portable radio or an mp3 player and listen to music or news and enjoy the fresh air.
I have been singing all my life and lack of testosterone has not affected it, although I have to warm up more carefully than before and make sure I keep hydrated. I guess like most things at our age (72 in my case), it's use it or lose it.
On. Casodex monotherapy testosterone can increase up to 50%. Least invasive therapy for psa recurrent cancer. Sids effects are minimal. Get T checked to confirm. rocco
Hi, my name is Lynn, my husband was put on casodex at age 65, did well for nine years. He is 74 young now, cancer came back this past year with a vengeance, taxotere chemo did not work, Zytaga, nor Xtand. Just had a cancerous lymph node removed waiting for test results and maybe, hopefully will have the right mutation for him to go on this certain clinicial trial??
I'm having my fingers crossed for you and your husband! There are many medications for prostate cancer and I'm positive they can find something that will work for your husband! Just keep on fighting!
Thank you so much! I also have fingers crossed and rooting for you, your Dad and all that are fighting this nansty cancer!! We were told after the LN was removed that now without even getting the results as of yet the oncologist mentioned chemo every week for the rest of my husbands life, he's not to happy about that with the side effects had had on taxotere that Failed him.
I'm so hoping that there will be another treatment after the biopsy comes back,
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