Zytiga recycling, intermittent treatment approach posted earlier, designed to extend treatment duration.

[tom82]

I am just starting on an initial Zytiga treatment. My current PSA is 29.0. (My overall treatment history since my June 2015 diagnosis is in my profile and is current through January 2018.)

Has anyone incorporated the Zytiga recycling approach of the following article (posted earlier by Patrick) into their overall PCa treatment? If so, with or without testosterone supplementation?

nature.com/articles/s41467-...

Any comments from oncologists? Any further information available on this subject from other sources? As always, your help is much appreciated.

My prayers go out to all of you in this difficult journey!

Thanks, Tom

[tom82]

This "dynamic" Zytiga treatment approach would appear to have significant potential to continue lowering a patient's PSA over a longer period of time than the current constant dosage treatments!

The link in the above post is not working. Please use the following link. Sorry for the inconvenience.

nature.com/articles/s41467-...

[LDW88]

Hi, curious if you've experimented with this? My father has been on Zytiga for just under one year with quick results (first couple months) and his oncologist now wants him to go off and continue Lupron every 3 months. He was on Zytiga + Lupron as first line of defense. MD thinks results will hold for a while and once PSA rises can restart Zytiga with same response. Not entirely in line with the article suggesting stop earlier before PSA is too low allowing sensitive cells to regenerate. Appreciate any info, thx!