re: liver and lung mets....."Ipilimum... - Advanced Prostate...

Advanced Prostate Cancer

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re: liver and lung mets....."Ipilimumab with radiation may slow late-stage cancer tumor growth" - Sept 25, 2017

JLS1 profile image
JLS1
2 Replies

I didn't see anyone post this, so I thought I'd share:

Ipilimumab with radiation may slow late-stage cancer tumor growth

September 25, 2017

healio.com/hematology-oncol...

"The combination of ipilimumab and stereotactic body radiotherapy delivered sequentially demonstrated promising response rates and survival in patients with solid tumors and metastatic lung or liver lesions, according to prospective phase 2 study results presented at the American Society for Radiation Oncology Annual Meeting."

".....Additionally, this study provides fascinating data suggesting that there may be a difference in the immunological response of a metastasis in the lung vs. the liver......"

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JLS1
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ctarleton profile image
ctarleton

FYI, there is also a Clinical Trial that is trying "Ipi" (aka Yervoy) following Provenge in the context of prostate cancer.

clinicaltrials.gov/ct2/show...

And, unfortunately, a completed Trial that used "Ipi" vs. placebo in advanced prostate cancer, but did not show an Overall Survival benefit, while causing serious adverse events, and even deaths during the study.

ascopubs.org/doi/full/10.12...

Charles

MelaniePaul profile image
MelaniePaul

Wow, that sounds interesting. We will forward this to our oncologist.

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