Hello Everyone, I'm new to this site. My 63 year old husband was diagnosed with metastatic prostate cancer in January, 2015. He was initially given oral meds (Casodex, Zytiga and Xtandi). He's due for his 4th cyle of chemo (Taxotere) in the coming weeks. His PSA has gone down to 26; however, the side effects have become progressively worse (lack of taste, fatigue, achy, hair loss, etc.) The hardest part is the uncertainty of it all. Doctors tend to be rather vague at times. Can anyone shed some light on what we should expect in the weeks after chemo therapy has ended? How long do patients typically mantain a lower PSA after treatment?