I'm 51, had gleason of 4+4 and 4+3 in two cores. Treated with IMRT and brachy, which didn't work. PSA went from 8 before treatment to 38 after treatment. NIH scans showed abdominal aortic lymph nodes involvement and some other spots in the prostate. Started Lupron in Aug 2016 and PSA was last at 0.09 for a few months in a row. Thinking about a few options to pursue such as: Zytiga or intermittent pause to let cancer be identified on scans and possibly do a biopsy for tissue to use in genetic testing/precision medicine or just stay on the Lupron alone until it fails and then try something else (sequential approach).