casodex side effect: recently i posted... - Advanced Prostate...

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casodex side effect

joeoconnell profile image
12 Replies

recently i posted that i had side effects from taking casodex in that it made me cry on an ongoing basis. i quit taking it some time ago but i asked if anyone else had this experience. being as i never heard from anyone i began to question if i was successful in posting the question, or no one else has had this problem, so i thought i'd have another go at it ( asking )

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joeoconnell profile image
joeoconnell
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erjlg3 profile image
erjlg3

My lg says he cries at commercials now and other shows. He's on more than 1 hormone treatment though. We have a cutoff time here. No sadness talked about here after 6:30 p.m. ;) YOU ARE NOT ALONE ;)

Good wishes Joe. I must have missed this or I would have answered before. Smiles.

Jackie

herb1 profile image
herb1

Joe, depression in various forms is a frequently reported side effect of any androgen control/decrease mechanism. We do seem to become more emotional. The treatment: exercise and, I guess, if needed, medications. A change in medications might help, but I don't see discontinuing these protective treatments (casodex, LHRH agents) as an option. See my other discussion: estradiol patches may be worth looking into as an alternative...and then discussing with your docs.

Herb S.

joeoconnell profile image
joeoconnell in reply to herb1

Herb, thanks for your input. you of course would have no way of knowing the severity of what i'm talking about. it was so sever i told the doc, it will be a cold day in hell before i take that again. the quality of my life was zero . i have a predisposition for depression to start with.

bluepacifica profile image
bluepacifica

@Joe: I am so sorry you're going through this. I, also, didn't see your original post. My husband was on Casodex for 3 years as well as getting his regular Lupron shots. Lexipro helped for sure. Best wishes. Joy

joeoconnell profile image
joeoconnell in reply to bluepacifica

thanks for your concern. i just now discovered your post

bluepacifica profile image
bluepacifica in reply to joeoconnell

Please know that you have many friends here. I will say, if you are not currently on an kind of anti-depressant, I would seriously consider it, especially if you have a predisposition. My husband had been on Lexipro, our doctor switched him to Celexa which did not seem to work. When my husband had his dna tested we discovered that 4 antidepressants, Celexa and Paxil were in that group, that would not work. Les is back on Lexipro.

joeoconnell profile image
joeoconnell in reply to bluepacifica

i am on bupropion which is a big help. my regular doc told me they can help manage brain chemistry but not hormonal chemistry

bluepacifica profile image
bluepacifica in reply to joeoconnell

I remember when they said that after the first Lupron shot it's like my husband's body was going 70 mph forward, and then got slammed into reverse. Lexipro was a life-saver for him. And me. Yes, the whole experience was horrible, but after 12 years and stage IV, he's still here, leading a normal of a life as possible. Of course, getting to live on Kauai here in Hawaii doesn't hurt. ;)

20PeteG16 profile image
20PeteG16

JoeC,

"No way in in hell!" As a disabled veteran I tought I experienced a bit of hell, but ADT took me back to deep depression, nightmares and more...

Active surveillance is a must for me. It's the comorbidity that we more often scrum to. Without ADT, cancer is manageable for me.

PeteG

joeoconnell profile image
joeoconnell

thanks Pete for your input ... i too am a disabled vet

MyDad76 profile image
MyDad76

I know it is an old thread, but I wondered if someone would have any other side effects to add? My father lost a lot of muscles, is more easily fatigued and also has some voice changes. Recently he started experiencing some lower back pain - we will have it checked but I hope it is not related to disease progression.

joeoconnell profile image
joeoconnell in reply to MyDad76

i too hope it is not related to the progression of the disease

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