I've been on Lupron for four months now (2nd injection) and my PSA dropped from 139 to 0.28 with tolerable side effects, no metastasis. Doctors say I'm not eligible for surgery so later this week I will begin a series of 48 focused radiation treatments at Sloan Kettering. I've been told most men don't experience side effects for the first two weeks but beyond that no idea. Since I have a long trip by public transportation in New York City to the treatment center I'm wondering how the treatments might affect my ability to get around. I realize no one can predict my body's reaction but the experience of others in my situation would be helpful if I need to make alternative transportation plans.