Hi, I’m new to the group. I’m raising my granddaughter who has ADHD, SPD, and may be ASD. She is 8 years old. She takes 15mg of Ritalin 3 times a day, Wellbutrin 150mg in the morning, and .2 clonidine, 5 mg melatonin, and 50 mg trazadone at night. Usually this works well. Every few weeks the sleep meds don’t work and she is up all night. She trashed the living room and draws all over herself, and sometimes other things, as well as sing loudly to the tv. I leave the room to try and remove additional stimulus but after a while she starts seeking me out and can be physically aggressive. She will laugh while she is attacking me because she thinks my reactions are funny. Anyone have suggestions? I get so frustrated I don’t know what to do.