How do I choose between Cyberknife (S... - Active Surveillan...

Active Surveillance - Prostate Cancer

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How do I choose between Cyberknife (SBRT) monotherapy vs HDR Brachytherapy+EBRT?

FiguringOut profile image
3 Replies

M59, Gleason 4+3 (second opinion confirmed by Jonathan Epstein at John Hopkins), PSA7.8 average past 1 year, T2C stage. Haven't been operated or radiated before.

Currently am being offered:

1) 5 fraction Cyberknife (SBRT) therapy that is concentrated to the prostate.

2) 1 time high dose rate Bracytherapy combined with 5 week EBRT radiation therapy.

None of docs believe ADT is necessary as of now.

I can't make the choice.

On one hand, SBRT efficacy is often compared with level of Bracyhtherapy.

It is apparently very similar in results, but I'm worried if Brachy+EBRT won't be way more effective ensuring that pelvic lymph nodes are also captured in the beam?

After all my case has a rather high recurrence rate after Radical Prostatectomy according to nonograms, however if lymph nodes are radiated, doesn't that lower the risk dramatically?

And how can Cyberknife compared in efficacy when it radiates only the prostate?

There are some talks that SBRT high dose radiation is more effective in killing cancer, but it can't kill mets outside prosate, can it now? While EBRT can.

Cyberknife would be ideal solution and its close to home. Brachy+EBRT requires 5 week living in another country.

What do you think, which case would you choose in my situation?

Pros and cons of each?

What do you think of met risks with Cyberknife?

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FiguringOut
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RMontana profile image
RMontana

I just saw this today; I think this is what you are looking for. From what UCLA says SBRT vs EBRT (IMRT / VMRT) is a wash...I learned a bit here as well...good to know about the BCF rates for both treatments...take a look...Cheers

Go to YouTube: look up "Stereotactic Body Radiotherapy for Prostate Cancer | Amar Kishan, MD | UCLAMDChat"

I cant send the LINK...TNX

FiguringOut profile image
FiguringOut in reply toRMontana

What do you mean "is wash"? Are equal?

RMontana profile image
RMontana in reply toFiguringOut

...sorry, yes the article basically says the two are equal in results...short term the SGRT may have a bit higher incidence of complication (e.g. bladder and colon) but long term the study says that it and EBRT / IMRT have the same rates...watch the YouTube...I had 34 sessions at 2 Gy for a total of 68 Gy (IMRT / VMRT), but talked to some men who at the time were having SBRT for the reasons that they did not want to spend that much time under the machine...why did I not do SBRT? My Doctor did not recommend it and I wanted to error on the side of providing enough time and radiation to make sure I got all the cells that may be left in my fossa bed...I also had a RP (robot surgery) and had a Persistent PSA (0.13) at 6 weeks...they did not get it all with the surgery...am now post RT (radiation) and doing my PSA checks to see if at last they did kill all my PCa cells; wont know for a few months...if they did not, then its back to treatment...Cheers

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