Is nucala approved as an egpa treatment in Europe

[Cathywp]

I am wondering if nucala is approved as a treatment for egpa in the UK? It was approved in dec 2017 in the United States, but in Canada my new doctor tells me it is only approved as a treatment for asthma at 100 mg and not approved as a treatment for egpa which would require 300 mg. I have heard it has very little side effects and can eliminate the need for prednizone....or at least reduce the prednizone to a very low dose. I wonder what I , as a patient , can do to help get this drug approved. Does anyone have experience with this medication?

[PMRpro]

Judging by this:

gsk.com/en-gb/media/press-r...

as of 30 August 2018 it is NOT approved in Europe as they only mention the US, Canada and Japan.

I seriously doubt a single patient can hurry up the approval process - it is lengthy, complicated and expensive. You could try contacting GSK.

But Brexit will very likely have a major effect on whether it can be used in the UK.

[Cathywp in reply to PMRpro]

I live in Canada and it is only approved for asthma here, not for egpa

[Riff1954 in reply to Cathywp]

My wife has EGPA and we live in the U.K. She is on Nucala but only at 100mg which our consultant says shows every sign of being as effective as the higher dose. She was able to get this treatment as she 'qualified' under the rules for Eosinophilic Asthma

[John_Mills Volunteer]

It has only been approved by NICE here in the U.K. to treat Eosinophilic Asthma. It has not been considered yet for EGPA but it is likely that it will be appraised by NICE in the near future.

[Reboundman in reply to John_Mills]

Hi John - do you know whether the 'near future' has arrived yet - has there been any upfatye on Nacula from NICE or where could I find out?

many thanks

[John_Mills Volunteer in reply to Reboundman]

As far as I know NICE suspended it in 2018 but will make further investigations

[Reboundman in reply to John_Mills]

Hi John - thanks for reply. Can I check did you mean you will make further investigations or that NICE plan to?

[John_Mills Volunteer]

Myself