I have GPA and started Rituximab just under 12 weeks ago. My inflammatory markers are normal and ANCA result now negative, pred down to 15mg daily. Despite all this I still have sinus symptoms, aches and pains and feel generally unwell all of the time. I am keen to know if others have experienced this and whether things improve further over the next few months, due my next infusion in Dec - its a 6 monthly regime. Any experiences greatly received.