A very, very interesting paper has just been published. In essence, it suggests that thyroid hormone helps with the repair of almost every tissue it has been tested with.
One of the characteristics of hypothyroidism is the large number of symptoms – and the way they seem to worsen and increase in number as the disease progresses. If, as this suggests, thyroid hormone is necessary for tissue to repair, then lack of thyroid hormone could allow the damage to remain and accumulate – rather than being repaired?
It sometimes feels as if every type of medic except endocrinologists are becoming more fully aware of the impact of low thyroid hormone levels. Surely this cannot really be the case, but quite a few patient experiences point in this direction.
Happily, the full paper is freely and readily available here:
I recommend viewing Table 1 within it.
The PubMed listing is here:
J Thyroid Res. 2013;2013:312104. doi: 10.1155/2013/312104. Epub 2013 Feb 25.
Thyroid hormone and tissue repair: new tricks for an old hormone?
Mourouzis I, Politi E, Pantos C.
Department of Pharmacology, University of Athens, 75 Mikras Asias Avenue, Goudi, 11527 Athens, Greece.
Although the role of thyroid hormone during embryonic development has long been recognized, its role later in adult life remains largely unknown. However, several lines of evidence show that thyroid hormone is crucial to the response to stress and to poststress recovery and repair. Along this line, TH administration in almost every tissue resulted in tissue repair after various injuries including ischemia, chemical insults, induction of inflammation, or exposure to radiation. This novel action may be of therapeutic relevance, and thyroid hormone may constitute a paradigm for pharmacologic-induced tissue repair/regeneration.
PMID: 23533950 [PubMed - in process]