I wish I could tell you my latest bloods, but GP is sitting on them. However, she wants me to start carbimazole 5mg and prednisone 20mg (for 3 days). She mentioned my T3 was 6.3 and T4 was within range but that’s exactly what it was last month so I’m not even sure that’s the up to date result. I also have hashi ABs so this could all be the transient hyper phase of that.
I’m very wary to start meds before absolutely knowing the results. Also, slightly worried it’s a GP prescribing and not an endo (can’t see endo til May 2025).
Would you take meds and see if symptoms improve or wait for more specialist diagnosis?
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i put this on your other post but i'll copy it here ,, it's useful for others to see timeline , previous results etc .
looking back
3 months ago:
TSH 3.8 ( no T4 done).
2 mths later :
TSH: 0.1 (0.3 - 5)
T4: 15.7 (7 - 20)
Ferritin: 130 (15 - 20) interestingly, results from 2 months ago showed ferritin at 57.
symptoms still there including hoarse voice, hair dropping etc/ A&E vist , tachycardia/. According to the scales in A&E I’ve lost 6lbs in 4 weeks without trying, lost appetite.
prescribed beta blockers ,,, helping with palpitations / tremor
2 wks later (medichecks):
TSH 0.05 [0.27 -4.2]
fT4 25 [12-22]
fT3 5.8 [3.1- 6.8] TPOab 250 [<34]
high cortisol.
then endo letter : healthunlocked.com/thyroidu... ~ asks GP to retest in 2mths to see pattern.
So .... apart from beta blockers which you have already , there is not much to do but wait for next test unfortunately..... regardless of whether this is early /mild graves that is potentially worsening and might end up properly hyper ... or just early hashimotos that is wobbling around a bit and will eventually go hypo at some point later on , it doesn't actually make any difference in practical terms at this point...... even if they did a TSI test today and it was positive , they (presumably) won't risk giving you antithyroid drugs unless T4/ T3 are shown to be consistently over range ... (because they risk potentially serious side effects on liver) and you obviously don't need any levo at this point .... so what happens next will depend on the results of the next test .
The only tools they have to fix thyroid problems ( whatever the cause is) are antithyroid drugs , levo , beta blockers , or remove / destroy thyroid ..... or wait and see ... that's the lot.
when you get next test in ? about a month .... it should hopefully be clearer what is happening .
This is a Summary of Product Characteristics document for one prednisolone product approved in the UK. I can't see a single relevant indication for its use alongside carbimazole.
Your antibodies are high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).
Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormone working
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances.
Most common by far is gluten.
Dairy is second most common.
A trial of strictly gluten free diet is always worth doing
Only 5% of Hashimoto’s patients test positive for coeliac but a further 81% of Hashimoto’s patients who try gluten free diet find noticeable or significant improvement or find it’s essential
A strictly gluten free diet helps or is essential due to gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and may slowly lower TPO antibodies
While still eating high gluten diet ask GP for coeliac blood test first as per NICE Guidelines
The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported
In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned
Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.
Similarly few months later consider trying dairy free too.
Approx 50-60% find dairy free beneficial
With loads of vegan dairy alternatives these days it’s not as difficult as in the past
Thanks for this. Would TPOabs not be this high if it were Graves? I know my T4/T3s are normal/just over so that kind of rules out Graves according to @greygoose.
That’s why I’m reticent to take carbimazole from GP when it’s potentially going to flip-flop about due to Hashimotos. I already suffer hyper/hypo symptoms as it is!
I’ve heard of beta blockers being prescribed alongside carbimazole but when I was diagnosed my GP started me off on carb and booked for me to see an endo she said I couldn’t have beta blockers because I have asthma, but something makes me think people who are given them would probably take them for more than three days. The three days sounds very strange doesn’t it.
When I was first diagnosed I came home to a message from my GP to say that my thyroid was very hyperactive with antibodies, she had (1) booked me to see an endo, (2) had left a prescription at reception for me and (3) come back after four weeks for more blood tests.
It was three months before I eventually saw and endo but my surgery file shares with my local hospital and after four weeks I had blood tests done and I got a letter from my endo telling me to get more carbimazole and double the amount I was taking so there was some contact with the endo even though I never saw her. Perhaps it’s the same with your GP and that could be why your GP has prescribed the carb. As for the prednisolone I have no idea about that and I haven’t heard of it before. . Have you been booked in to see an endo?
You need to get and keep copies of all your tests. You are entitled to them.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Super confusing test results - pls help 
GP Visit and HRT worries 😰
Research into getting T3 meds 
Need some advise regarding Carbimazole, Graves disease
Advice please
