chest pain when changing carbimzole dose

[Ruby8810]

hi my daughters carbimazole dose has been lowered from 10mg to 5. She is complaining of some chest pain. Has anyone experienced this? This has occurred before and was in the midst of thyroid systems so gp didn’t think it was a concern but I feel it’s linked to the medication

[Regenallotment Ambassador]

Tagging PurpleNails for help with your question. Although chest pain is one of those …. Head to A&E immediately symptoms so just saying that too 🙏

[Ruby8810 in reply to Regenallotment]

it comes and goes again. We have been to several doctors and a&e before. Had ecg done. No problems found. Just unsure if it’s a common thing with altering the medication

[pennyannie]

Hello Ruby :

What has your daughter been diagnosed with ?

Carbimazole is an Anti Thyroid drug and generally prescribed when there is a diagnosis of Graves Disease -

Is this case - please confirm which antibodies were found positive in her initial blood test and can you share her TSH + T3 + T4 readings and ranges at diagnosis

and more recently when the drug dose was adjusted down to just 5mcg a day :

You may find the following research of interest if my guess on diagnosis is correct :

pubmed.ncbi.nlm.nih.gov/338...

ncbi.nlm.nih.gov/pubmed/306...

The most rounded of all I have researched is that of Elaine Moore - books and website -

elaine-moore.com

[SlowDragon Administrator]

what were her results that prompted dose reduction in Carbimazole

She needs bloods retested 6 weeks after dose change

ESSENTIAL to test vitamin D, folate, B12 and ferritin

Ideally full iron panel including ferritin

Low iron/ferritin often causes tight chest and/or breathlessness

What vitamin supplements is she taking

Has she definitely had Graves’ disease confirmed by testing TSI or Trab antibodies

[humanbean]

Low iron/ferritin can cause chest pain. So I would definitely ask for your daughter to get a full iron panel.

healthline.com/health/anemi...

mayoclinic.org/diseases-con...