No - the MHRA expressly say that the identity will be redacted. And, from a personal point of view, I think that is right. No-one should have to reveal their identity just in order to ask a question. However, I think our curiosity it understandable.
I don't think it is possible to identify from what we know. Whilst I wouldn't have worded it like that, and certainly not pushed that I was a medical researcher (I'm not in that sense), the basic question is one I might have asked.
Fascinating! This could be someone taking T3 and hoping to prevent it being withdrawn from them. It's a shame there's no way of seeing the published paper which the person attached.
I wish. I admire your optimism. Given that it is a medical researcher and the poor odds of that medical researcher also having hypothyroidism and also being a poor converter of T4 to T3, the chances are low, unfortunately.
Initially upon reading this post, I thought you, Helvella, had written this foi request. Once it; became clear that you hadn't, my interest was piqued (I love a mystery). So the first thing I did was a Google Scholar search, viz:google.com/search?q=Google+...
All this tells us though is which researchers have an interest in this area and are potential candidates for being the 'medical researcher' in question.
helvella RedApple
I've tagged you, as I've edited my reply since you 'liked' it.
True, I too thought that. However, from their comment about having published a paper, I then thought it likely that the researcher in question had an historic interest.
Unfortunately the list of possible researchers includes at least one who is anti T3. By the way, sorry for the edits in my first reply, I'm on my phone and flicking back and forth through tabs on Google and I didn't want to lose what I had written so far.
Like BB001, I thought initially you had requested the information. The request seems to be in the same sort of time frame as a question mark being raised about the prescriber at Roseway labs prescribing T3 , going forwards. A forum member clarified their position a few days ago, in that they cannot prescribe T3 in the first instance, going forward. They will continue T3 if initially instigated by an Endocrinologist.
I did read a while ago that a well known retired from the NHS- Endo , based in Oxford, well known researcher in Wales (I think), and maybe someone from UCL ??? had had a meeting and come to the conclusion that the NHS needed to build their own manufacturing factory or something of that ilk, to keep the price of medicines down and to ensure sufficient supplies always available. I believe T3 was the prime example used for their way of thinking, and the previous price debacle with T3. The Oxford based Endo is pro T3, not anti T3.
I wondered if the scenario with the NHS factory-type thing they believed needed to be set up, had actually come to fruition? The reason being that , after Labour came to power, and possibly maybe the day after the budget?????( ish), Rachel Reeves was shown visiting a new Manufacturing Accord Facility in Newcastle, and I think it was referred to as NHS???? It was either a photograph in a Saturday issue of the Daily Mail, or on TV. Although I believe NHS was mentioned, it was an Accord factory, and definately in Newcastle. If I can summon up the energy I'll have a look and see if I can find anything.
EDIT:
If you Google "New Accord NHS Factory In Newcastle", there are articles written at the start of this month re." Government -backed deal will enable Accord to manufacture autoimmune and oncology medicines to the NHS".
NHS manufacturing does look like an appropriate response to some parts of price gouging by companies. But I think an awful lot of us here think that importing Thybon Henning would have been an excellent step.
That product has remained at a stable price (in Germany) throughout the over-charging scandal.
Yes, Accord did buy a manufacturing facility in Newcastle (area). Though when journalists get into saying what the company's plans are, I become even more sceptical than usual.
I have no idea about the actual layout and buildings. The Fawdon site was a Sanofi facility, so is this a new building, or newly fitted out? I suspect Accord got it at a relatively low price. And now £50 million of our money, they seem to be doing OK! (No criticism intended - I don't know enough to take a view on the issue.)
Going back to liothyronine, Accord did apply for and receive approval for their own product - back in 2022. (And why I added it to my UK medicines document.)
Re. you saying Accord have a license for 20 mcg Lio- that is disturbing. I am splitting 20 mcg Thybon Henning Lio. The sole importer in the UK , I think is Clinigen? A forum member posted quite recently that , I have a funny feeling, might have been that Clinigen are no longer importing Thybon Henning Lio, T3. For this to happen it may be that the Accord 20mcg Lio you refer to will be the forced alternative, which avoids importing a product.
There have been a few members looking to continue Thybon Henning T4 , which I know you personally liked on past use. They may have been Irish. This seems to be no longer imported. BUT, I think someone did say Clinigen , who will likely be the supplier of Roseway Labs-supplied, Thybon Henning T3, will no longer be importing it. Perhaps they are no longer allowed to import, as Accord T3 20 mcg will be the forced alternative.
Accord have had a licence since 2022. It is difficult to second-guess what is happening. But I agree that we have reason for some concern but until we know more, it is difficult to see what we can usefully do or say.
Their T4 product is usually called L-Thyroxin Henning.
An irony in here - that the new Accord plant was purchased from Sanofi who own Henning.
Yes, I thought from previous posts you have made, that Sanofi own Henning!
I know the Australian female testosterone product which is unlicensed in the UK, has been going through the process of getting MHRA approval for years now. I think I read something to the effect that the MHRA have to invite the company to apply for approval of the product in the UK, rather than the company itself being able to apply to the MHRA???
If this is the case, Thybon is unlicensed in the UK because the MHRA would need to invite them to go through the process of having it approved in the UK. As Accord is normally supplied by Boots as Almus, as well as ACCORD in its own right (rebranding), it seems to be being allowed too much dominance in the market, through the back door. Perhaps Henning don't want the hassle of seeking approval, even if invited to apply for approval.
No - companies can apply to the MHRA but the MHRA doesn't go out and ask companies to apply. (There may be special circumstances where funny things happen. I wish we had some members who really knew these things instead of us having to try to divine what happens.)
We know Glenmark T4 would likely be universally tolerated, and could effectively corner the market. I pointed this out to Glenmark in correspondence. Despite this , it has only been available for a few months in two separate years. They must have a quid pro quo agreement re. supply with other drug companies/suppliers/ manufacturers(you scratch my back, I'll scratch yours).
Perhaps Thybon have a similar , quid pro quo agreement with other manufacturers , where they have agreed not to seek MHRA approval in the UK for T3, in exchange for favourable market conditions elsewhere, or with another drug. It is the way of the world , nowadays.
I think Thybon T3 is about to become unobtainable in the UK , as Accord T3 will be seen to be an available "suitable licensed product . " BUT, we still shouldn't be expected to change products , as we know only too well.
I have just gone through the ingredients of Accord T3 and Thybon T3 to see if they are like for like. The ingredients/ excipients are not all the same, unless some are alternative names for the same thing? Of those which are different:
In Thybon, not Accord: Cornstarch( also has the pregelatinised Cornstarch), Sodium Carbonate, In German: Natriumthiosulfat 5 H2O (Ph.Eur), Silica,fumed, Castor Oil, hydrogenated.
Looks as though the excipients in Accord are different from Thybon???
Edit: 7 years ago , Thybon had Disodiumthiosulfate-5-water ( Dinatriumthiosulfat-5-wasser). It is currently, in German, Natriumthiosulfat 5 H2O (Ph.Eur).The translation is Sodium thiosulfate 5 H2O. This might be the same thing, or different????
Edited: Current box of Thybon Liothyronine hydrochloride :
Sorry, having a brain foggy day! Current box of Thybon from Roseway came from Mawdsleys International Services. Don't know if Mawdsleys' get it from Clinigen or can import in their right, or not.
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