Taking levothyroxine with food: I'm currently on... - Thyroid UK

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Taking levothyroxine with food

Blackcat122 profile image
17 Replies

I'm currently on 25mcg levothyroxine, I'm having difficulty swallowing them, they're so tiny they just seem to stick in my throat even with lots of water.Rang the doctors receptionist to ask for liquid form, but told no, it's too expensive, and to speak to a pharmacist.

I spoke to him today, and he recommended putting the tablet into a small jelly sweet and swallowing it.

I queried that I thought it had to be taken on an empty stomach, but he said it would be OK.

I'm curious to see if anyone else take theirs like that?

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17 Replies
TiggerMe profile image
TiggerMeAmbassador

Could you not crush the tablet up and add it to a shot of water, ideally empty stomach for an hour after or 2 hours before if evening dosing... so no sweets not advised 🫤

Blackcat122 profile image
Blackcat122 in reply toTiggerMe

Thanks for your reply. That sounds more sensibleThanks Susan

Dancer57 profile image
Dancer57

I have never been able to swallow tablets whole. I crush them on a teaspoon with some water, never been a problem.

Blackcat122 profile image
Blackcat122 in reply toDancer57

Thanks Dancer, I'll give that a try

Oakwood4321 profile image
Oakwood4321

hi Blackcat122 I had exactly the same problem with the Levo tiny tablets. I asked gp for liquid Levo and was also told no due to the cost, similar suggestions were made to me - take it with a spoon of jam or piece of bread. I did persist asking and had it prescribed and had it for a couple of years now.

I also take small Roma t3 capsules and swallowing them isn’t a problem. For me it was the tiny dry Levo pills that just seemed to stay lodged in my throat.

Blackcat122 profile image
Blackcat122 in reply toOakwood4321

Hi Oakwood. I'm pleased you've found a solution, and you've been prescribed the liquid. I'm hoping that as I move onto a higher dose, they may be bigger and easier to swallow. Like you said, they're so small and dry they just seem to lodge in your throat and go nowhere fast!!Susan

Oakwood4321 profile image
Oakwood4321 in reply toBlackcat122

Thanks Susan. One tip I found which helped a bit was to try swallowing the pills with water drunk from a sport cap bottle, it seemed to wash them down with a bit more force 😊

helvella profile image
helvellaAdministrator

Before there were any levothyroxine oral solutions, several of the Patient Information Leaflets for levothyroxine actually said that if you have swallowing issues, or for infants, you could disperse the tablet in a little water.

While I think they no longer say that, it was a matter of policy - not the the tablets have changed. :-)

The best plan might be to disperse with a little water, swallow, then swish out with a bit more water and swallow that as well. Total amount of water doesn't need to be very much. But make sure none of the tablet gets left behind.

Blackcat122 profile image
Blackcat122 in reply tohelvella

Thanks Helvella.I'll give that a try.

Brigland27 profile image
Brigland27

No I take my 100mg tablet with a good swig of water that I keep next to my bed when I 1st wake at around 5am daily

Blackcat122 profile image
Blackcat122 in reply toBrigland27

I've tried that but it still sticks in my throat 😔

Brigland27 profile image
Brigland27 in reply toBlackcat122

Aw you'd be best just sticking to what your doctor recommended then, hope it works for you Blackcat122

Blackcat122 profile image
Blackcat122 in reply toBrigland27

Just bought a pill crusher from boots. Fingers crossed🤞

SlowDragon profile image
SlowDragonAdministrator

Difficulty swallowing is a hypo symptom

25mcg is a tiny starter dose and can make you feel more hypo

How old are you

Standard starter dose is 50mcg ……but starting on 25mcg recommended if over 65

Book next blood test for early morning

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

you will need several further increases in Levo over coming months

which brand of Levo are you currently taking

Blackcat122 profile image
Blackcat122 in reply toSlowDragon

Hi SlowdragonI'm 66 so I suppose I'm on the correct starter dose, been on mercury 25 mcg for 2 weeks now

I initially felt well, but this past week I've felt unwell again, tired, dizzy, aching legs, shivery.

I'm due a blood test in 6 weeks so I'll take notice of your recommendations

I've read on this forum about initially feeling more hypo when starting levothyroxine

Thanks Susan

SlowDragon profile image
SlowDragonAdministrator in reply toBlackcat122

Yes…levo initially and briefly tops up your own thyroid hormone levels, but very quickly pituitary notices the Levo dose and TSH reduces…..and your own thyroid output drops …..so you become more reliant on Levo…..and that’s why symptoms return/get worse as you approach 6-8 weeks after a dose change……ready for next increase to 50mcg daily

Retest again in another 2-3 months

most people need to increase levothyroxine dose slowly upwards in 25mcg steps (retesting 6-8 weeks after each increase) until eventually on, or somewhere near full replacement dose (typically 1.6mcg levothyroxine per kilo of your weight per day)

cks.nice.org.uk/topics/hypo...

bnf.nice.org.uk/drugs/levot...

nhs.uk/medicines/levothyrox...

Some people need a bit less than guidelines, some a bit more

TSH should be under 2 as an absolute maximum when on levothyroxine

gponline.com/endocrinology-...

Graph showing median TSH in healthy population is 1-1.5

web.archive.org/web/2004060...

Comprehensive list of references for needing LOW TSH on levothyroxine

healthunlocked.com/thyroidu....

onlinelibrary.wiley.com/doi...

If symptoms of hypothyroidism persist despite normalisation of TSH, the dose of levothyroxine can be titrated further to place the TSH in the lower part of the reference range or even slightly below (i.e., TSH: 0.1–2.0 mU/L), but avoiding TSH < 0.1 mU/L. Use of alternate day dosing of different levothyroxine strengths may be needed to achieve this (e.g., 100 mcg for 4 days; 125 mcg for 3 days weekly).

sciencedirect.com/science/a...

The optimal daily dose in overt hypothyroidism is 1·5–1·8 μg per kg of bodyweight, rounded to the nearest 25 μg.

Far too often GP thinks patient is only a “little bit hypo” so just give them a little bit of levothyroxine

It doesn’t work like that

Blackcat122 profile image
Blackcat122 in reply toSlowDragon

Thanks SlowDragon. Very informativeSusan

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