Falling normal range tsh ft4 : I've had bone... - Thyroid UK

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Falling normal range tsh ft4

Cookiemunster profile image
16 Replies

I've had bone marrow transplants for a blood disorder so get bloodwoork done.I've noticed that my TSH is falling however is at 2.21 so in norm range. My Ft4 is 12.4 pmol which is borderline normal. Both tsh ft4 have been falling when I look at the trend chart since Oct 23.

Nobody has raised a concern with me yet however I am getting concerned.

I do have unusual symptoms I have difficulties losing weight, I get freezing cold at times temperature intolerant, raised cholesterol.

I also have PCOS which can explain some of this.

I also have horrible pains in my legs with a tendency to swell and feel stressed alot of the time. I get bouts of dramatic low mood.

I don't know what to do, i feel like if I raised this with the gp I'd be laughed out the door! As my labs are in range.

Any insight would be helpful x

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Cookiemunster profile image
Cookiemunster
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greygoose profile image
greygoose

Hi Cookiemunster, welcome to the forum. :)

Can you give us the range for that FT4, please? Ranges vary from lab to lab, so we need those that came with your results. But, if the range is 12-22 - as it often is - then your FT4 is very low.

Your TSH may be falling, but it's still too high, ans suggests that your thyroid is struggling. But doctors won't take any notice of it until it drops below range.

TSH is a pituitary hormone, so could the bone marrow transplants be affecting that? Or, on the other hand, skewing the blood test results? I don't know. But it is a point to raise with your doctor. And if your doctor is a decent human being, s/he won't laught your concerns out the door, that would be very unprofessional. Start by talking about your symptoms and then voice your concern about the dropping levels.

High cholesterol does suggest that your FT3 is low, but unlikely you'll get that tested on the NHS (if you're in the UK). So, maybe full thyroid testing privately would be a good idea, if you can. :)

Cookiemunster profile image
Cookiemunster in reply togreygoose

Here is an image of my results

Range and results
Cookiemunster profile image
Cookiemunster in reply toCookiemunster

See falling

Trend
Cookiemunster profile image
Cookiemunster in reply toCookiemunster

Tsh lowered

And again falling
greygoose profile image
greygoose in reply toCookiemunster

Your FT4 is only 14.81% through the range, which is very low. It should be at least 50%. But most doctors think that if it's anywhere within the range it's got to be ok. How wrong they are!

But, of course, without the FT3 you don't have the full picture.

What time of day was the blood draw for that test? Do you always get the blood draw at the same time of day? Because TSH changes throughout the day, being highest before 9 am, and lowest around midday.

Even so, with such a low FT4, the TSH should be much higher, so either there's a pituitary problem, or something skewing your results. Are your bloods always done at the same lab?

Cookiemunster profile image
Cookiemunster in reply togreygoose

Yes same in house lab I'm in the UK BTW.This was an afternoon draw 13:15pm

Cookiemunster profile image
Cookiemunster in reply togreygoose

The Oct reading was 12:40pm

greygoose profile image
greygoose in reply toCookiemunster

OK, so your TSH would be pretty low at those times - especially 12:40 pm. But, if they're not done at the same time every time, you can't compare them. So, that could be one reason why the TSH appears to be dropping.

Even so, I think it's worth mentioning to your doctor because your FT4 is so very low.

Cookiemunster profile image
Cookiemunster

I'd also say I'm finished treatment for around 8 yrs now

greygoose profile image
greygoose in reply toCookiemunster

Oh, OK, but, perhaps it could have had an effect on your pituitary reducing production of hormones, I don't know. In any case, your pituitary doesn't seem to be working correctly - what we call Secondary Hypo. To get a clearer idea about that you would need to test TSH/FT4/FT3, at the same time each time, at about two monthly intervals for a while to see how things progress. If it is Sencondary Hypo, the TSH will stay around the same level, whilst the FT4/3 slowly drop further and further.

Cookiemunster profile image
Cookiemunster in reply togreygoose

Ok thank you, I will ask of my nurse specialist and see how I go. I find the hospital better for referring on to specialists than my gp

greygoose profile image
greygoose in reply toCookiemunster

OK, but I would be very surprised if she's even ever heard of Secondary Hypo. :(

Cookiemunster profile image
Cookiemunster in reply togreygoose

Maybe your right, but I will talk to her about my results and symptoms in the 1st instance. She's recently referred me back to gynae and rheumatology due to heavy periods and pains particularly in my legs, I'm also always complaining about fatigue to her, all of these things together are looking highly suspect especially when you throw in my weight and poor response to diet changes, and weird chills I get.

greygoose profile image
greygoose in reply toCookiemunster

Certainly sounds as if you're hypo!

SlowDragon profile image
SlowDragonAdministrator

your blood disorder…..just wondering if this is autoimmune ?

having one autoimmune disease makes others more likely

For full Thyroid evaluation you need TSH, FT4 and FT3 tested

Also both TPO and TG thyroid antibodies tested at least once

Very important to test vitamin D, folate, ferritin and B12

Low vitamin levels are extremely common when hypothyroid, especially with autoimmune thyroid disease

About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high TPO and/or high TG thyroid antibodies

Autoimmune thyroid disease with goitre is Hashimoto’s

Autoimmune thyroid disease without goitre is Ord’s thyroiditis.

Both are autoimmune and generally called Hashimoto’s.

Significant minority of Hashimoto’s patients only have high TG antibodies (thyroglobulin)

20% of autoimmune thyroid patients never have high thyroid antibodies and ultrasound scan of thyroid can get diagnosis

In U.K. medics hardly ever refer to autoimmune thyroid disease as Hashimoto’s (or Ord’s thyroiditis)

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

Post all about what time of day to test

healthunlocked.com/thyroidu...

Testing options and includes money off codes for private testing

thyroiduk.org/testing/

Medichecks Thyroid plus BOTH TPO and TG antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes BOTH TPO and TG antibodies, cortisol and vitamins

bluehorizonbloodtests.co.uk...

Only do private testing early Monday or Tuesday morning.

Link about thyroid blood tests

thyroiduk.org/testing/thyro...

Link about Hashimoto’s

thyroiduk.org/hypothyroid-b...

Symptoms of hypothyroidism

thyroiduk.org/signs-and-sym...

Tips on how to do DIY finger prick test

support.medichecks.com/hc/e...

Medichecks and BH also offer private blood draw at clinic near you, or private nurse to your own home…..for an extra fee

Cookiemunster profile image
Cookiemunster in reply toSlowDragon

I am in remission for Myelodysplasia, I am also hypermobile and suspect heds also difficult to get dx in the UK! I have also got allergies and tend to be sensitive to side effects and have very strange allergy triggers. My sister has a thyroid issue I don't know what and can't find out. My brother has lupus.

My vit d has been low in the past, I supplement high dose. My ferritin is high due to blood transfusion induced iron overload.

My folate also drops from time to time

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