Just written a new blog which is currently not much more than an introduction and link to a major nutrient review - all accessible (open access).
Well worth a read. The linked paper (not my blog).
helvella - Anti-Nutrients including Goitrogens
A short discussion about goitrogens and other anti-nutrients and link to a major review paper.
Not exactly misleading but open to wrong interpretations:
Goitrogens are substances, most often just foods as non-foods tend to be viewed as toxins, which impair the production of thyroid hormones and can cause or contribute to the formation of goitres.
I think it's important to explain that they impair the production of thyroid hormones by limiting the amount of iodine they thyroid can absorb. The thyroid then forms a goitre to expand its surface area to absorb more iodine.
I agree that impairment of iodine uptake is a well-known mechanism, it appears to be why the classic goitrogens (such as brassicas - cabbage family) have their impact.
But it appears that both soy (in its direct effect within the thyroid) and millet have their effects by impairing the function of thyroid peroxidase enzyme.
In that sentence, I was just trying to be helpful to anyone unfamiliar with the word goitrogen.
OK, I didn't know that about soy and millet. (I will refrain from making the usual joke about budgerigars 
)
And I'd very much rather someone pointed an issue out than kept quiet!
You made me go away, check what I thought I knew, and add another link to my blog post. All good things.
Fascinating, thank you. Its good to have all of the things that can affect Thyroid Function and absorption of thyroid meds in one place.
It would be good to have an idiots guide for us with hypothyroidism eg you can eat or drink this and that but only if boiled for 60 mins or served with iodised salt or whatever. There’s a lot there and I really couldn’t understand what was important and what wasn’t. But thanks for posting!
Most of it said that the benefits of eating the foods in moderation likely outweighed any likely negatives.
However, don't base your diet on any known goitrogen.
And, in some cases, cooking reduces the impact but this might not always be so.
Also, it is patent that much of the science is animal-based and humans are different. Many of the goitrogens appear to vary in impact depending on other factors. The effects of the other substances discussed, the ones that have non-goitrogenic effects, could be at least as significant on our health. Things like their effects on our ability to absorb iron, zinc, copper.
Goitrogens versus gluten free versus diet for boosting immune system...
