Hypo on Aristo

[Bean101]

I have been taking 62.5 mcg mercury pharma plus 15T3 for a couple of years

Every time I try and increase the Thyroxine I get itchy eyes and a runny nose ( with stomach pain) so eventually I got a prescription for Aristo.. but since being on it I am so hypothyroid, I’m struggling to walk and spend most of my day in bed.. I have been on 75mcg for about 8 weeks.. when I stopped it for a couple of days it lifted.

So I am not sure what to do.. I could go back onto Mercury pharma and manage to do more than what I’m doing now.. but with the allergies and stomach issues I would rather find another option.

I have tried Accord, Wockhart, Thybon Henning T4 and all made me more hypo.

I don’t want to take T3 only

I did think about having liquid thyroxine compounded but not sure how expensive or accurate that would be

I have terrible exhaustion and a passing out feeling.. any advice I would appreciate.. Many thanks x

[SlowDragon Administrator]

I have been on 75mcg for about 8 weeks..

You need to test 6-8 weeks after being on constant unchanging dose and brand levothyroxine

Very common to initially feel better when stop levothyroxine…..before becoming significantly worse

What are your vitamin levels

What vitamin supplements are you taking

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

T3 ….day before test split T3 as 2 or 3 smaller doses spread through the day, with last 5mcg dose approximately 8-12 hours before test

[TiggerMe Ambassador]

So you don't get the reaction issues with Aristo perhaps you just need to increase it?

What were your last results?

[Bean101 in reply to TiggerMe]

No I don’t have any issues taking it.. just feeling so exhausted on it.. maybe it’s weaker than mercury pharma

I haven’t done any blood tests on Aristo.. I have a blood kit here

[TiggerMe Ambassador in reply to Bean101]

Some people have said they find it milder, I looked back at you old results and your fT4 barely makes it above 50% so I'm thinking you really need to try it around 75% which is often near the sweet spot 🤗

[Bean101 in reply to TiggerMe]

Thank you.. I’m blaming the Aristo but maybe I’m not on enough.. I will test then increase x

[SlowDragon Administrator]

post 4 months ago

healthunlocked.com/thyroidu...

Low Folate, poor B12

Have you tested since

[Bean101 in reply to SlowDragon]

I will get them tested.. if B12 low and folate would it make such a difference in tolerating thyroid meds?

I have started folate drops and extra B12 sublingual mouth spray

[SlowDragon Administrator in reply to Bean101]

would it make such a difference in tolerating thyroid meds?

Yes ….Low vitamin levels makes it difficult to tolerate replacement thyroid hormones

Rather than just folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

If Vegetarian or vegan likely to need ongoing separate B12 few times a week

Highly effective B12 drops

natureprovides.com/products...

Difference between folate and folic acid

healthline.com/nutrition/fo...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule)

Thorne currently difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

Igennus B complex popular option too. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose

Post discussing different B complex

healthunlocked.com/thyroidu...

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

helvella.blogspot.com/p/hel...

[Bean101 in reply to SlowDragon]

I struggle to tolerate supplements so I was going to try the igennus super B complex effervescent.. and start with half tablet!

Thank you and everyone for the advice x

[Jefner]

I got given Aristo a couple of months ago and thought I would try it but started to feel hypo on it after a week or so. thankfully back on my Accord

[Bean101 in reply to Jefner]

Thank you.. I will give it a couple of weeks on the higher dose and see if any improvements..