posted earlier with my results ,just got this back now , what does this mean please

[Prosecco1997]

Thyroid peroxidase ab's 89 ku/L [< 34.0]; Antibody screen positive.; Outside reference range

[greygoose]

It means you have Autoimmune Thyroitis - aka Hashi's - and that is the cause of your hypothyroidism. Do you know about Hashi's?

[Prosecco1997 in reply to greygoose]

No I don’t , read bits cause I thought I had it but doctors said very unlikely , is this why I feel so awful Thankyou for your reply

[greygoose in reply to Prosecco1997]

No, you feel awful because your FT3 is low. It wasn't tested but if your FT4 is low, your FT3 is also going to be low.

And, you feel awful because of your low nutrient levels. The Hashi's itself doesn't cause the symptoms, it's the hypothyroidism it causes that cause the symptoms.

Anyway, just shows how wrong doctors can be! Especially where thyroid is concerned. Why did they think it was likely you didn't have it?

Hashi's is an autoimmune disease, where the immune system slowly destroys the thyroid, mistaking it for the enemy. The difference between Hashi's and hypothyroidism caused by other things is that levels can be very unstable, sometimes swinging between hypo and false 'hyper' and back again. And doctors don't understand this, so it's as well if the patient does! But, eventually, the thyroid will be killed off and you will become entirely dependant on exogenous hormone.

Hashi's people often also have Coeliac Disease, or are highly sentive to gluten. Which is why it is recommended to get tested for Coeliac, and even if that's negative, try a gluten-free diet, which can drastically reduce symptoms. It doesn't help everyone but worth a try. Also, some are better when dairy-freee. So, that's worth a try, too. But not at the same time as trialing gluten-free, or you won't know which one helps.

[greygoose in reply to greygoose]

I’m realy suffering with my throat feels like something pushing on a nerve , and I can’t walk properly sometimes awful feeling , does this sound like hashimotos

Hashi's itself doesn't have any specific symptoms. The symptoms are caused by low thyroid hormone levels. But, with Hashi's your thyroid could be inflammed, which could feel the way you describe.

Did your doctor not do a CRP blood test? CRP is an inflammation marker and should always be done when testing ferritin, because inflammation can falsely elevate ferritin levels. Your ferritin is very high, so could be that you have high CRP, meaning that you have inflammation somewhere in your body. Could be your thyroid inflammed.

Not being able to walk properly could very well be due to your low B12. That needs attention urgently.

[Prosecco1997 in reply to greygoose]

Thyroid peroxidase ab's 89 ku/L [< 34.0]; Antibody screen positive.; Outside reference range

[Prosecco1997 in reply to Prosecco1997]

Full blood count

Haemoglobin concentration 150 g/L [120.0 - 150.0]

Total white blood count 4.8 10*9/L [4.0 - 10.0]

Platelet count - observation 289 10*9/L [150.0 - 400.0]

Haematocrit 47 % [36.0 - 46.0]; Outside reference range

Red blood cell count 4.64 10*12/L [3.8 - 4.8]

Mean cell volume 100 fL [83.0 - 101.0]

Mean cell haemoglobin level 32.0 pg [27.0 - 32.0]

Neutrophil count 2.45 10*9/L [1.8 - 7.4]

Lymphocyte count 1.36 10*9/L [1.1 - 3.5]

Monocyte count - observation 0.44 10*9/L [0.21 - 0.92]

Eosinophil count - observation 0.50 10*9/L [0.02 - 0.67]

Basophil count 0.08 10*9/L [0.0 - 0.13]

Nucleated red blood cell count 0.00 10*9/L; If advice is required regarding the interpretation of

abnormal full blood count results please see pathfinder

(haematology/documents) or the haematology NGH intranet

page.Serum sodium level 137 mmol/L [133.0 - 146.0]

Serum potassium level 4.4 mmol/L [3.5 - 5.3]

Serum creatinine level 51 umol/L [45.0 - 84.0]

eGFR using creatinine (CKD-EPI) per 1.73 square metres > 90 mL/min

Serum total protein level 68 g/L [60.0 - 80.0]

Serum albumin level 47 g/L [35.0 - 50.0]

Serum alkaline phosphatase level 52 iu/L [30.0 - 130.0]

Serum bilirubin level 11 umol/L [< 21.0]

Serum alanine aminotransferase level 20 iu/L [5.0 - 33.0]

Acute kidney injury warning stage 0; AKI Stage 0

[greygoose in reply to Prosecco1997]

Yes, you put that above. It's positive for Hashi's.

There is not test for CRP in that list. Amazing!

[Prosecco1997 in reply to greygoose]

I’m going to see a thyroid doctor on Monday , do you think I will be put on a higher dose of levethyroxine or different medication

[greygoose in reply to Prosecco1997]

Well, you certainly won't be put on a different medication! But an increase will depend on how thyroid-savvy your doctor is. As both your FT4 and TSH are within range, he might consider his job is done - most of them are like that, not a clue! You may have to insist that you need an increase because you still don't feel good.

You have to be pro-active when you have thyroid problems, because doctors know so little about it. You cannot just rely on them knowing what they're doing because most of them don't. They treat by numbers, whilst not fully understanding those numbers, rather than the patient herself.

[Prosecco1997 in reply to greygoose]

Full blood count

Haemoglobin concentration 150 g/L [120.0 - 150.0]

Total white blood count 4.8 10*9/L [4.0 - 10.0]

Platelet count - observation 289 10*9/L [150.0 - 400.0]

Haematocrit 47 % [36.0 - 46.0]; Outside reference range

Red blood cell count 4.64 10*12/L [3.8 - 4.8]

Mean cell volume 100 fL [83.0 - 101.0]

Mean cell haemoglobin level 32.0 pg [27.0 - 32.0]

Neutrophil count 2.45 10*9/L [1.8 - 7.4]

Lymphocyte count 1.36 10*9/L [1.1 - 3.5]

Monocyte count - observation 0.44 10*9/L [0.21 - 0.92]

Eosinophil count - observation 0.50 10*9/L [0.02 - 0.67]

Basophil count 0.08 10*9/L [0.0 - 0.13]

Nucleated red blood cell count 0.00 10*9/L; If advice is required regarding the interpretation of

abnormal full blood count results please see pathfinder

(haematology/documents) or the haematology NGH intranet

page.Serum sodium level 137 mmol/L [133.0 - 146.0]

Serum potassium level 4.4 mmol/L [3.5 - 5.3]

Serum creatinine level 51 umol/L [45.0 - 84.0]

eGFR using creatinine (CKD-EPI) per 1.73 square metres > 90 mL/min

Serum total protein level 68 g/L [60.0 - 80.0]

Serum albumin level 47 g/L [35.0 - 50.0]

Serum alkaline phosphatase level 52 iu/L [30.0 - 130.0]

Serum bilirubin level 11 umol/L [< 21.0]

Serum alanine aminotransferase level 20 iu/L [5.0 - 33.0]

Acute kidney injury warning stage 0; AKI Stage 0

[Charlie-Farley]

Not sure if it will help you but I documented my journey and explained the misconceptions doctors have on certain (most) things thyroid related. Click on

My face to see my bio and I made some posts to provide information- a sort of a case study.

Just to warn you most endocrinologists are diabetes specialists, ergo not thyroid specialists and from reading on this forum seem to know little more than the average GP, but are way more confident in that little knowledge because they are ‘Endos’.

[FallingInReverse in reply to Charlie-Farley]

Thanks for your profile story, I wanted to hit a “like” button on so many sentences as I read it : )

[SlowDragon Administrator]

High TPO antibodies confirms the cause of your hypothyroidism is autoimmune

About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high thyroid antibodies

Autoimmune thyroid disease with goitre is Hashimoto’s

Autoimmune thyroid disease without goitre is Ord’s thyroiditis.

Both are autoimmune and generally called Hashimoto’s.

Low vitamin levels are extremely common when hypothyroid, especially with autoimmune thyroid disease

20% of autoimmune thyroid patients never have high thyroid antibodies and ultrasound scan of thyroid can get diagnosis

In U.K. medics hardly ever refer to autoimmune thyroid disease as Hashimoto’s (or Ord’s thyroiditis)

They ignore the autoimmune aspect and just treat the subsequent hypothyroidism

However GP should test for coeliac disease at diagnosis

nice.org.uk/guidance/ng20/c...

1 Recognition of coeliac disease

1.1.1 Offer serological testing for coeliac disease to:

people with any of the following:

persistent unexplained abdominal or gastrointestinal symptoms

faltering growth

prolonged fatigue

unexpected weight loss

severe or persistent mouth ulcers

unexplained iron, vitamin B12 or folate deficiency

type 1 diabetes, at diagnosis

autoimmune thyroid disease, at diagnosis

irritable bowel syndrome (in adults)

first‑degree relatives of people with coeliac disease.

thyroid and vitamin results here

You are in need of next dose increase in levothyroxine and vitamin D, folate and B12 all need improvement

healthunlocked.com/thyroidu...

[Prosecco1997 in reply to SlowDragon]

Hello just got back from seeing thyroid doctor , he did not increase my levethyroxine? Said my antibodies were realy high , requesting I have a throat scan , and dosnt think I need to be seen by him no more , I was told I have hashimotos , he mentioned a full blood count fibromyalgia, and rheumatology, all very confusing, I asked how to stop the high antibodies from attacking my thyroid and he said you can’t

[SlowDragon Administrator in reply to Prosecco1997]

work on improving your vitamin D, folate and B12 levels as detailed in previous post

healthunlocked.com/thyroidu...

Has GP done, or are they doing coeliac blood test

Get tested BEFORE trialing strictly gluten free

Antibodies are not the disease, they are cleaning up after each attack

Many people find they can reduce autoimmune attacks/reduce inflammation by

Gluten Free Diet

Dairy Free Diet

Plus OPTIMAL Vitamin levels can help improve conversion of Ft4 (levothyroxine) to Ft3 (active hormone)