Timing of taking T3 - by day : Am writing this... - Thyroid UK

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Timing of taking T3 - by day

HowNowWhatNow profile image
20 Replies

Am writing this out while under the grip of a blazing migraine but as am not fit for doing much else, thought I’d come here to write a note for anyone here taking T3.

I have been taking it for a year or so and without thinking about why, always took it at the same time as my levothyroxine - before bed.

Recently - travel / children’s school holidays / carelessness - I changed that routine around and I now take it in the mornings.

Since I have had a thyroid condition I have felt as if my body has a curfew. Any time from 5 onwards, I start being slow, low on energy and staid in the mind, and switch off much much earlier. As in, don’t have presence of mind to think, plan and get organised for the day / week / months ahead, over and above the most urgent things. Or to fully be in the moment at all. And so I don’t feel myself.

However, I notice a big difference in all that staidness since taking T3 in the evenings. I actually keep going and have life left in the evenings now, and don’t collapse into a puddle. Of course I hope this lasts because it’s great to be reminded of what my old self could do again.

Do others feel the same way? Do you have any other tips re: timing if T3 or on staying awake and compos mentis in the evenings?

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HowNowWhatNow
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20 Replies
SlowDragon profile image
SlowDragonAdministrator

How much levothyroxine and how much T3 are you taking

Many people find it better to split T3 as 2 or 3 smaller doses spread through the day

10-12 hours apart if 2 doses

Roughly equal 8 hour intervals if 3 doses

And day before test ALWAYS split as 3 doses

Looking at previous posts

healthunlocked.com/thyroidu...

Your ferritin was dire

Have you had iron infusion yet

Vitamin D insufficient

How much vitamin D are you taking

B12 and folate levels?

Low vitamin levels suggest perhaps under medicated for thyroid

Migraine/headaches are hypothyroid symptoms

all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

On T3 - day before test split T3 as 2 or 3 smaller doses spread through the day with last dose 8-12 hours before test

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

List of private testing options and money off codes

thyroiduk.org/getting-a-dia...

Medichecks Thyroid plus antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes antibodies, cortisol and vitamins

bluehorizonbloodtests.co.uk...

Only do private testing early Monday or Tuesday morning.

Link about thyroid blood tests

thyroiduk.org/getting-a-dia...

Symptoms of hypothyroidism

thyroiduk.org/wp-content/up...

Tips on how to do DIY finger prick test

healthunlocked.com/thyroidu...

Medichecks and BH also offer private blood draw at clinic near you, or private nurse to your own home…..for an extra fee

HowNowWhatNow profile image
HowNowWhatNow in reply to SlowDragon

Thanks.

I had an infusion done in June, only 6 months after my GP referred me to the hospital to get it done.

I can no longer tolerate any iron tablets at all and am not yet in the menopause, so it is starting to look - my hospital’s haematology unit is remarkably inefficient, so I can’t rely on them for the regular infusions they told me at first I would have - as if I will have to have a hysterectomy.

Before this recent infusion my ferritin level was at 6 and HB was also sub-normal. If it had only been my ferritin that was so low. I would not have got the infusion. Hospitals are HB obsessed and ferritin not-bothered.

When last checked my vitamin D was only one point above the normal range cut-off. Sorry not to have it to hand. 51, is what I remember.

I take half a tablet of T3 once daily. Am not at home so can’t tell you what size that is.

I am experiencing lots of symptoms in the gut, gynaecological and bladder area at the moment. All are intractable. I had hoped that stopping taking iron would make them better but no.

It would be a good idea to get my thyroid markers checked again.

Thank you for your patience in reading my old posts and asking all the right questions.

HowNowWhatNow profile image
HowNowWhatNow in reply to HowNowWhatNow

It is a lovely afternoon and I just went for a walk. My headache symptoms were improved by doing so. Movement is so often a good thing.

Quite a few of my current symptoms are those of autonomic systems not working. They’ve all gone on holiday.

Tythrop profile image
Tythrop in reply to HowNowWhatNow

Interested in Gyne/ bladder sptoms.poor you ,but is it slow or restricted flow by any chance?

HowNowWhatNow profile image
HowNowWhatNow in reply to Tythrop

That’s part of it, yes.

SlowDragon profile image
SlowDragonAdministrator in reply to HowNowWhatNow

When last checked my vitamin D was only one point above the normal range cut-off. Sorry not to have it to hand. 51, is what I remember.

Normal is not optimal

You will need to improve vitamin D by supplementing

GP will often only prescribe to bring vitamin D levels to 50nmol.

Some areas will prescribe to bring levels to 75nmol or even 80nmol

leedsformulary.nhs.uk/docs/...

GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)

mm.wirral.nhs.uk/document_u...

But with Hashimoto’s, improving to around 80nmol or 100nmol by self supplementing may be better

pubmed.ncbi.nlm.nih.gov/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly via NHS private testing service when supplementing

vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function.

There’s a version made that also contains vitamin K2 Mk7.

One spray = 1000iu

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need, with thyroid issues we frequently need higher dose than average

Suggest you try 2000iu daily and retest in 2-3 months. Might need higher dose, especially in winter

Vitamin D and thyroid disease

grassrootshealth.net/blog/t...

Vitamin D may prevent Autoimmune disease

newscientist.com/article/23...

Web links about taking important cofactors - magnesium and Vit K2-MK7

Magnesium best taken in the afternoon or evening, but must be four hours away from levothyroxine

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

HowNowWhatNow profile image
HowNowWhatNow in reply to SlowDragon

The strange thing is that I do take vitamin D. Not every day but at least twice a week, mostly about 3 or 4 times.

I take it in the form of Osteocare, a formula containing Vit D and a few other complementary vitamins.

Obviously I need to take it every day and to take more of it.

SlowDragon profile image
SlowDragonAdministrator in reply to HowNowWhatNow

Better to just take vitamin D, a separate magnesium

Ideally…..Test Zinc before supplementing

SlowDragon profile image
SlowDragonAdministrator in reply to HowNowWhatNow

My own regime

T3 as 3 x 5mcg per day roughly every 8 hours

Dose 6.20am, 2-3pm and 11pm

Levothyroxine at 11pm too

Always same brand levothyroxine

Always same brand T3

Strictly gluten and strictly dairy free and avoid all soya

Daily supplements after breakfast

Vitamin D - 5000iu (maintains vitamin D at 100nmol)

Daily vitamin B complex (Thorne or Igennus)

Once week selenium and zinc

Daily Thorne Magnesium about 6pm

Only taken 29 years to work it out!

HowNowWhatNow profile image
HowNowWhatNow in reply to SlowDragon

Very thorough.

Do you set alarms to remind you what to do when?

SlowDragon profile image
SlowDragonAdministrator in reply to HowNowWhatNow

Alarm for 6.20am …..immediately go back to sleep

Otherwise no …I just have a daily routine

Vitamins after breakfast

Magnesium after dinner

Mid afternoon T3 ….time can vary depending of what’s happening in the day

Weekly pill dispensers for levothyroxine and another for vitamins

Day pill dispenser for T3

Lalatoot profile image
Lalatoot

I take a dose of levo and a dose of liothyronine t3 on waking and then another dose of each at bedtime.It is whatever suits the individual and their routine.

HowNowWhatNow profile image
HowNowWhatNow in reply to Lalatoot

Glad to hear you have found a regimen you’ve put some thought and research into and works for you.

I hadn’t expected such a big difference from changing my T3 routine as I have had.

McPammy profile image
McPammy

I take my T3 on waking. Then a second dose at 3pm. Taking once a day would make me feel very low late afternoon. I also split my levothyroxine dose into 2 doses per day.

HowNowWhatNow profile image
HowNowWhatNow in reply to McPammy

Thanks McPammy.

How did you arrive at this system?

I would like to know if anyone reading has monitored their changes in routine using outward objective markers like … body temperature? .. did you?

McPammy profile image
McPammy in reply to HowNowWhatNow

I’ve never checked my temp. Just how I feel. I feel much better feeding T3 and T4 medications more smoothly into my system rather than flooding it once a day.

my private only endocrinologist prescribed T3 lio twice a day. I decided to also split my T4 levo.

HowNowWhatNow profile image
HowNowWhatNow in reply to McPammy

Oh that’s interesting - that your endo recommended this split dosage.

Thank you.

I am going to try this.

shaws profile image
shawsAdministrator

I take one daily dose of T3 with one glass of water when I awake a.m. and wait an hour before I have breakfast.

I follow the advice given by a scientist/doctor and expert on liothyronine (T3). Dr John Lowe was also an adviser to Thyroiduk before his death due to an accident.

Dr John Lowe didn't split his dose of T3 and he stated that T3 has to saturate all of the T3 receptor cells and it then sends out 'waves' throughout the day.

tpauk.com/main/article/dr-j...

HowNowWhatNow profile image
HowNowWhatNow in reply to shaws

Thank you.

Was he listened to by the Simon Pearces (if that is his name - I mean the Mr BTF guy) of his day? Or was he a renegade agent of truth?

This is what I’m doing and it’s working for me.

Do you also take levo-?

shaws profile image
shawsAdministrator in reply to HowNowWhatNow

No I don't take levo as it didn't improve my health. It gave me immense palpitations and I and husband - tried to control palps by giving me ice-cold water to sip during the night.

The Cardiologistist at the local hospital had to record my overnight palpitations (and I assume it enabled him to make a decision and to report to GP or endocrinologist)..

T3 alone has eliminated my symptoms. and my body is calm and I feel well and my heart is also calm.

Dr John Lowe was a scientist and doctor. He was aso an expert in how best to restore patients health. He was also an Adviser to Thyroiduk.. Dr John Lowe had a very bad fall that caused his demise due to a bleed on his brain due to the fall. He is badly missed.

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