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Items which should not routinely be prescribed in primary care: policy guidance ❗️❗️❗️

helvella profile image
helvellaAdministrator
53 Replies

This was published yesterday and applies in England.

Please follow the link in order to see this as intended - I have edited out references to medicines other than liothyronine.

Date published: 3 August, 2023

Date last updated: 3 August, 2023

Medicine, Primary care

Items which should not routinely be prescribed in primary care: policy guidance

This policy guidance provides recommendations for items which should not be prescribed in primary care because they are unsafe, ineffective for some or all patients, or are not cost-effective. It is for integrated care boards, other organisations commissioning services, and prescribing healthcare professionals, and updates and replaces the guidance published in June 2019.

This policy guidance is issued as general guidance under s14Z51 of the NHS Act 2006 to reduce unwarranted variation, improve patient outcomes and provide value for money for the NHS. It provides recommendations for items which should not routinely be prescribed in primary care because:

there are significant safety concerns with the item

there is a lack of robust evidence of clinical effectiveness for the item

the item is clinically effective but more cost-effective interventions are available

the item is clinically effective but deemed a low priority for NHS funding.

These items include medicines, devices, food supplements and other treatments.

This guidance is for:

integrated care boards (ICBs)

organisations commissioning services.

prescribing healthcare professionals.

It updates and replaces the guidance published in June 2019. More detail about how this guidance was developed and what has been updated can be found in the frequently asked questions.

About the recommendations

The policy recommendations are grouped under two categories:

Items where no prescribing is appropriate (no exceptions apply).

Items where prescribing may be appropriate in some exceptional circumstances.

The following policy recommendations apply to all items in both categories:

do not initiate in primary care

deprescribe in patients currently prescribed this item.

The following policy recommendations apply to some items in the second category due to one or more exceptions:

prescribe only if no other item or intervention is clinically appropriate.

prescribe only if no other item or intervention is available.

prescribe only if the item is for an indication named in this guidance.

Additional prescribing guidance is provided for some items, including alternatives and where a multidisciplinary approach is required. Prescribers should also follow local prescribing policies.

The recommendations do not override the individual responsibility of healthcare professionals to support their patients in agreeing the most appropriate treatment options for them through taking a shared decision-making approach.

Policy recommendations

Items where no prescribing is appropriate (that is, no exceptions apply)

Items where no prescribing is appropriate because there are significant safety concerns or there is no evidence of clinical effectiveness for all patient populations.

Recommendations (2)

Do not initiate in primary care.

Deprescribe in patients currently prescribed this item.

Prescribe only if no other item or intervention is clinically appropriate.

Prescribe only if no other item or intervention is available.

Prescribe only if for an indication named in this guidance.

These recommendations apply to:

liothyronine:

follow NHS England prescribing advice on liothyronine when initiating or reviewing the prescribing of liothyronine

the recommendations do not apply to patients who have already been reviewed by an NHS consultant endocrinologist

all other patients currently taking liothyronine should be reviewed by an NHS consultant endocrinologist to determine future treatment plans

new patients with overt hypothyroidism whose symptoms persist on levothyroxine may be prescribed liothyronine after a 3-month or longer review by an NHS consultant endocrinologist

Further detail, including useful references and the rationale for an item’s inclusion, can be found in the Appendix.

Implementation

ICBs will need to make implementation decisions locally, ensuring they consider their legal duties to advance equality and have regard to reducing health inequalities.

Effective implementation of the policy recommendations requires engagement across primary and secondary care, and development and use of shared care arrangements where appropriate. ICBs should follow guidance on Shared care for medicines and Responsibility for prescribing between primary and secondary/tertiary care.

Support for patients who may request a change to their current prescription is also recommended.

To allow commissioners to monitor prescribing, dashboards showing current prescribing patterns for the items included in this guidance are available to them from NHS Business Services Authority (NHSBSA) in ePACT2, PrescQIPP and OpenPrescribing.net. Data on spend and volume is summarised by item and is available at regional, area team, integrated care system (ICS), primary care network (PCN) and practice level. When monitoring, the clinical exceptions defined in this guidance should be taken into account and care taken to ensure that zero prescribing goals are not used inappropriately.

england.nhs.uk/long-read/it...

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helvella
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53 Replies
helvella profile image
helvellaAdministrator

I'm not sure how much this changes. It needs to be read in conjunction with pre-existing guidance/rules. In many cases, I suspect it largely formalises the sad reality.

waveylines profile image
waveylines in reply tohelvella

Are they cracking down further on NDT Helvella? I live in fear of that happening... Lol.

I've checked. It's a bit vague on Armour (and no mention of Erfa). I think the same rules apply as per Liothyronine. Looks like they have cut out Erfa. If this is the case it's gone from different brands of NDT being prescribed on the NHS to now just one.

helvella profile image
helvellaAdministrator in reply towaveylines

Afraid I have no information at all.

Could be it is so rarely prescribed no-one is worrying too much at the moment.

Edit:

Armour Thyroid is expressly included in the detailed notes. See screenshots posted on this thread.

grumpyold profile image
grumpyold in reply tohelvella

I agree. A "sad reality" which makes my blood boil. 😡 I refused to jump through the NHS hoops and "went rogue", sourcing and self funding my own T3. What the NHS doth not provide, they cannot taketh away. Whatever happened to "from the cradle to the grave"?! 😟

waveylines profile image
waveylines in reply togrumpyold

Indeed grumpy old.... What happened indeed. I noticed the mention of natural products.... Hope that doesn't include B12 vials!Privatisation not so much through backdoor but overt....

Unfortunately I need Armour which is incredibly expensive to buy so if NHS cut that goodness help me.... doubt I could afford it.

arTistapple profile image
arTistapple in reply togrumpyold

However, can they remove our levo under those circumstances. Privately sourcing T3 that is?

grumpyold profile image
grumpyold in reply toarTistapple

Quite possibly.....which is why they don't know I do it. As far as they are aware, my blood results are from the levo the NHS allows me.

arTistapple profile image
arTistapple in reply togrumpyold

What if your TSH should change and become too suppressed for their comfort? It’s ridiculous we have to worry that TSH sometimes becomes irrecoverable, simply because we are being treated.

grumpyold profile image
grumpyold in reply toarTistapple

I have been on Metformin for 7 years so my TSH always appears suppressed. I did have to educate one GP at the practice who reduced my T4 because TSH was too low. Shocking that she didn't know that Metformin has this effect! Didn't even tell me she'd done it and I only found out when I went to the pharmacy to collect my prescription. They can't just do that! I went ballistic. She won't make that mistake again!

arTistapple profile image
arTistapple in reply togrumpyold

Good on you. I have a big mouth on the forum but in real life I find it difficult to deal with that level of arrogance in the very few minutes we are given (if we can get an appointment). I am probably going to employ complete avoidance tactics now. I was left alone for about 18 years after a heart attack, basically because they had no idea what to do with me as I had no plaque in my arteries. It’s quite easy to live beneath the radar. It’s only when you want help and can’t get it …… However if my TSH should become suppressed I am very aware of advice given by the administrators here and will definitely confront it in any way I can.

I have been very proud of our ancestors success in bringing about the NHS. I am definitely put to the test philosophically, in employing any ‘private’ services. I feel I am contributing to its demise. These guys are an utter disgrace and it should be that we can do something about it. It’s just not cricket.

waveylines profile image
waveylines in reply tohelvella

It says update from 2019 in brackets.

helvella profile image
helvellaAdministrator in reply towaveylines

At the top it says:

updates and replaces the guidance published in June 2019.

And in the details it says:

Liothyronine (including Armour Thyroid and liothyronine combination products) (updated 2023)

It does say 2019 several times re other specific parts of the document.

in reply tohelvella

I believe that to be true

helvella profile image
helvellaAdministrator

From same document - expressly about thyroid medicines.

Screenshot 1
helvella profile image
helvellaAdministrator in reply tohelvella

From same document - expressly about thyroid medicines.

Screenshot 2
waveylines profile image
waveylines in reply tohelvella

Thanks will look that doc up.I keep thinking about changing GP (mine have gone down the swanny as they have implemented a three stage process to get an appointment (on phone or face to face) or even any medical advice but I daren't incase it highlights being prescribed Armour.

helvella profile image
helvellaAdministrator

From same document - expressly about thyroid medicines.

Screenshot 3
arTistapple profile image
arTistapple in reply tohelvella

Thank you for posting this load of BULL. We know precisely how ‘they’ have set this up. No understanding but their understanding and their understanding is what counts. Really they are such a transparent bunch of cowboys.

Star13 profile image
Star13

I wonder how many GP Pharmacists will use this an an excuse to get their oar in!

pennyannie profile image
pennyannie

And unless I am mistaken - RAI the clear winner in the treatment stakes for Graves Disease !!

Though suggests further follow ups - why don't they use the research already in circulation :

pubmed.ncbi.nlm.nih.gov/338...

ncbi.nlm.nih.gov/pubmed/306...

What is the point other than the obvious ?

waveylines profile image
waveylines

Hi Helvella. Just a query. On Thyroid UK under Thyroid Hormone replacement, Dessicated Thyroid Extract I notice Armour isn't listed. Just wondering why? All the others are including the odd one or two no longer being produced.

RedApple profile image
RedAppleAdministrator in reply towaveylines

waveylines, You need to contact TUK about this as they deal with all the info that they put on their website. thyroiduk.org/about-thyroid...

waveylines profile image
waveylines in reply toRedApple

Thanks Red Apple. Problem resolved.

helvella profile image
helvellaAdministrator in reply towaveylines

I'm sorry, I have no idea!

Not sure where you are looking:

American and Canadian brands of NDT are now available in the UK. The American brands are Armour Thyroid, NatureThroid, WP Thyroid and NP Thyroid. There is one Canadian brand, ERFA Thyroid.

thyroiduk.org/if-you-are-hy...

Or did you mean here:

Manufacturer Allergan

Product Name Armour Thyroid – various strengths from 15mg (¼ grain) – 300mg (5 grains) Tablets (Lactose Free)

thyroiduk.org/if-you-are-hy...

That is because the company became Allergan and is now AbbVie.

Can't see why NatureThroid and WP Thyroid remain - except possibly as historical comments.

Calling out to Lyn:

lynmynott

waveylines profile image
waveylines in reply tohelvella

Ahh didn't realise it had changed manufacturers. Sorry. I'm prescribed Armour should've looked on the bottle... It does say Allergan! 🙄🙄

helvella profile image
helvellaAdministrator in reply towaveylines

Current USA PIL (equivalent) is on AbbVie's website but says Allergan at the bottom:

rxabbvie.com/pdf/armour_thy...

A little of the confusing history of Allergan: en.wikipedia.org/wiki/Allergan

waveylines profile image
waveylines in reply tohelvella

Confusing being the operative word!! Or maybe I'm just confused!! 😂😅😉

SilverAvocado profile image
SilverAvocado in reply tohelvella

Has NatureThroid been permanently discontinued now? I was thinking it would eventually come back, but I haven't been keeping very on top of it.

helvella profile image
helvellaAdministrator in reply toSilverAvocado

I think many of us have been assuming that for a long time.

And if you visit the company's website, there is no mention of desiccated thyroid.

rlclabs.com/

Plus their GetRealThyroid website effectively says nothing at all.

getrealthyroid.com/find-a-t...

Maybe the continuing existence of the website offers the tiniest glimmer of hope? Afraid I suspect they've already paid for it so there is no cost to it being allowed to remain. It used to say things about recall - but no longer. Maybe FDA only required that for a limited time?

McPammy profile image
McPammy

Very interesting and scary at the same time. I’m on combined liothyronine with liquid levothyroxine treatment for poor conversion T4 to T3. My NHS Endocrinologist recently called me into hospital very unusually to have full thyroid and many other blood tests along with a short synacthen test. I’m happy to say all test results were good. I’m very lucky I believe to be able to keep my levels adequate and my TSH in range. I think if it was out of range it might be a different story. Thinking now they may have been looking to move me off T3. My endocrinologist was very happy with my blood results and emphasised that I am extremely lucky to be prescribed liothyronine off the NHS. I did think ‘ lucky?’ I wouldn’t wish this disease on my worst enemy. But I guess I’m relieved to get the T3 help I eventually did after many years of feeling half a person on mono therapy levothyroxine.

waveylines profile image
waveylines in reply toMcPammy

Yes there is this weird idea that we have a choice.... like ahh I fancy a bit of chocolate for a treat. Such nonsense!!Smile sweetly and focus on the outcome. There's been a fair few times when I've gritted my teeth and smiled sweetly when I'd really like to tell them what I really think!! Lol... 😂🤣

TSH110 profile image
TSH110 in reply toMcPammy

lucky little girl - god it makes me mad they treat us like infants

jimh111 profile image
jimh111

Hasn't changed much but they seem to be putting more effort into obstructing T3 prescibing. As usual the patient representative is one tamed person from the BTF, a thyroid support group with a membership of just a few thousand. The BTF is effectively under the control of the BTA and so does not represent patients. They are still doing the old trick of referring to 'hypothyroidism' in general whilst laying down conditions that specifically apply only to primary hypothyroidism. e.g. insisting on TSH > 10.0. By doing this they are able to restrict research to primary hypothyroidism whereas other causes of impaired thyroid hormone action are far more likely to respond to T3 therapy.

I think we need to be more robust when responding to these attempts of perceived cost cutting.

arTistapple profile image
arTistapple in reply tojimh111

I do so agree!

TaraJR profile image
TaraJR in reply tojimh111

jimh111 on the back of this post, and the NHSE T3 guidance for prescribers - a little while ago you were talking about shared care agreements and you said "Shared decision making and consent are fundamental to good medical practice." This means it is part of the GMC rules doctors must follow.

The next section Shared decision making to comply... references "The Montgomery Judgement" which states: -

" Whether a risk is material is no longer determined according to the views of a “responsible body of medical men” but by the views of “a reasonable person in the patient’s position”. "

Note: this carries the force of law, it is not an advisory document.

This wording seemed so good, I saved it, but now I can't find the link on the NHSE shared care webpage! Please could you add it here?

jimh111 profile image
jimh111 in reply toTaraJR

helvella for interest.

The GMC states shared decision making is fundamental to Good Medical Practice here gmc-uk.org/professional-sta... . GMP is the rules doctors work under. (I haven't read this document yet).

NHS England details shared decision making and the Montgomery Judgement england.nhs.uk/personalised... . The Montgomery Judgement is similar to 'the man on the Clapham Omnibus', it is a legal concept that defines how cases should be decided based on what a normal sane person would do.

NHS England advice for liothyronine prescribers which includes shared decision making england.nhs.uk/long-read/li... .

This does not mean a doctor much follow a patient's wishes, doctors should prescribe only if they feel it is in the patient's interests, they are free to prescribe or not according to their medical opinion.

AKatieD profile image
AKatieD

60 now and will never be able to retire. What NHS won't prescribe, when I am entiitled to free prescriptions, would not be affordable on a pension.

About £200 per month for T3 from reliable source, supplements and testing. Plus another £100 for HRT, again as I can't take what the NHS offers.

Free universal healthcare no longer

arTistapple profile image
arTistapple in reply toAKatieD

It’s never been free. You pay every month through your wages and the tax system. I think the relevant quote is “Free at point of need”. All that means is you do not shell out cash before you are allowed on the operating table, as they do in the States.

We are very much entitled to the best care possible and this ‘negligence’ only amounts to the government (again your money and mine) having to shell out a lot more money further down the line, treating so-called Co-morbidities. I definitely would not trust these doctors with our hard earned cash. Many of these consultants imagine themselves to be accountants as well as brains of Britain. However in real life, accountants manage to put perfectly good businesses out of business, because they do not understand how business works. The banks are also responsible in this way too, and they are presently involved in huge legal cases from companies pushed out of business by their actions.

It’s about time these arrogant (insulated) doctors wake up to and understand their true responsibilities.

TSH110 profile image
TSH110 in reply toarTistapple

Free at the point of delivery no?

TSH110 profile image
TSH110

we’re doomed

How do they get away with it? Are there no checks of balances against these dreadful decisions or the people making them?

What about the patients?

looks like pure vindictiveness to me.

arTistapple profile image
arTistapple in reply toTSH110

TSH I have looked at this too and it seems to me the system is designed so they are their own checks and balances. It certainly feels like vindictiveness from our point of view (Professor Pierce has showed himself in public to be remarkably small minded) but camouflaged for any eyes that matter. Our eyes don’t matter. I guess most of the ‘checks and balances’will be relatively uneducated civil servants, or medics drafted in to cover their backs/get more money for their opinions/career step ups/and anyone who wants to put one in the eye for scientists who do not agree etc etc.

TSH110 profile image
TSH110 in reply toarTistapple

He’s a very good reason for reform to lessen his power. A menace to society posing as a doctor.

Did he chose endocrinology so he could torture women? Is that his kick making women suffer? He just invents the science to back up his malpractice. It’s sinister.

I doubt change is coming any time soon…

arTistapple profile image
arTistapple in reply toTSH110

I have a few suspicions myself.

TSH110 profile image
TSH110 in reply toarTistapple

Well look at that scoundrel Shipman….

arTistapple profile image
arTistapple in reply toTSH110

And it took so long to sort him out!

Tythrop profile image
Tythrop

the item is clinically effective but deemed a low priority for NHS funding.Could this be where Lio (t3)comes in ?

That poor converters are not high priority to NHS ..that making poorly people better are not a high priority...if this is their policy ,where does it end?

Is it bean counting as well,?

StitchFairy profile image
StitchFairy in reply toTythrop

Making poorly people better is not a priority in my experience. As long as the medication keeps you from dying, that what's important. QOL is a bonus that the NHS doesn't invest in for thyroud patients.

TSH110 profile image
TSH110 in reply toStitchFairy

even better if it keeps you from dying (up to a point) but causes so many issues you need a plethora of other medications to keep going - very cost effective for the NHS 🙄

it’s really great to know that we are NOT worth it

TSH110 profile image
TSH110 in reply toTythrop

One wonders what exactly is their purpose if it isn’t looking after the nations health, when they openly declare they are deliberately withholding effective treatment on the lie it saves money. Knowingly keeping people ill does not save money, it’s plain wicked and very wasteful and costly to the individual and society

Tythrop profile image
Tythrop in reply toTSH110

Knowingly keeping people ill ..this is so right ....but it is committee's and personless detached beauracy...the absence if empathy is ,I think, the big thing .

TSH110 profile image
TSH110 in reply toTythrop

tsh and bean counting is all they care about not real people with real problems they could help redress.

It will end in the richest getting good health care becarse they can afford it and the rest left to rot. The market will decide that.

We already have a sickly population and it will only get worse

Tythrop profile image
Tythrop in reply toTSH110

Yes to all,also the mental health suffering is hell

pennyannie profile image
pennyannie

mainam

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