Prospective programme linking thyroid stasis to... - Thyroid UK

Thyroid UK

139,479 members163,720 posts

Prospective programme linking thyroid stasis to cardiac health

diogenes profile image
diogenesRemembering
16 Replies

This is the preamble to a proposed series of papers that discuss linkages between thyroid health and cardiac health. It is started by my coworker Johannes Dietrich. Papers on this topic are invited to consider problems and solutions.

Thyroid hormones and cardiac arrhythmia

Preventive programs and the development of specific therapeutic measures have helped to significantly reduce the load of cardiovascular risk over the previous decades. This applies to both the epidemiology of cardiovascular disease on the population level and the prognosis of individual patients affected by chronic disease. However, a significant residual hazard, beyond traditional risk models, is persisting. This gap may be filled by recent research that rediscovered thyroid homeostasis as a major determinant of cardiovascular health. Current advances extend to large population-based studies that identified even variation of thyroid function within established population-based reference ranges to be significant risk factors for sudden cardiac death, malignant arrhythmia and other major endpoints. Hence, it is most timely that a “thyro-cardio centric” thematic topic has been selected for this journal in order to bring more insights into the effects of thyroid hormone levels on cardiac health and disease.

Thyroid hormones are among the key mediators affecting cardiovascular function. Although a close link between the thyroid and the heart is known for more than two centuries, it was the recent years that witnessed the emergence of a deeper physiological understanding of the thyro-cardiac axis. This progress was accelerated by the development of new methods in molecular biology, electrophysiology, systems medicine, computational statistics and bioinformatics. The exponential growth of the number of published papers on the thyroid-heart nexus underscores the dynamics of this still evolving interdisciplinary field. It is against this background that the editors have organized the scientific content of this special issue.

Articles in this research topic include basic research papers, results of clinical studies and review articles that give a comprehensive overview on state-of-the-art methodology and recent results from the interface between the biology of thyroid hormones and cardiovascular electrophysiology, paving the way to a better understanding and management of a remaining challenge in predictive, preventive and personalised medicine.

Written by
diogenes profile image
diogenes
Remembering
To view profiles and participate in discussions please or .
Read more about...
16 Replies
humanbean profile image
humanbean

One of the problems for hypothyroid patients is that palpitations and/or tachycardia are always, always, always associated with levels of thyroid hormones that are too high. So hypothyroid people find themselves undiagnosed or under-treated, probably on beta blockers and anti-depressants because they are assumed to be anxious.

But as is clear from many posts on this forum these problems are also very common when thyroid hormone levels are too low.

Doctors appear to have two lists of symptoms - one for hypothyroidism and one for hyperthyroidism, and never the twain shall meet.

TSH110 profile image
TSH110 in reply to humanbean

It’s deffo low thyroid hormones in my case that exacerbates angina. I presume low T3 given NDT quelled the palpitations and Levothyroxine made them worse. They were intermittent prior to diagnosis.

humanbean profile image
humanbean in reply to TSH110

I have occasional tachycardia which usually goes away with adequate T3. So the two things - low thyroid hormone levels and tachycardia/palpitations/arrhythmia - are definitely related for me too.

jgelliss profile image
jgelliss in reply to humanbean

Many are in the same camp.

jgelliss profile image
jgelliss in reply to humanbean

So well said . Thank you. I think that many with cardiac problems and more. May it be palpitations cholesterol high/low BP. Dr's choose to over look the Real Source of the problem.Bandaging the problems with all sorts of medications are much more lucrative for Dr's and Big Pharma.

Mollyfan profile image
Mollyfan in reply to humanbean

The only paper/case report I have managed to find that confirms this is pubmed.ncbi.nlm.nih.gov/303...

Anecdotally it seems palpitations and tachycardia are associated with both hypo and hyper.

humanbean profile image
humanbean in reply to Mollyfan

Yes, I agree. Doctors' assumptions about what are symptoms of hyperthyroidism and what are symptoms of hypothyroidism wouldn't match any symptoms lists created by patients.

TSH110 profile image
TSH110 in reply to humanbean

I had a right mixed bag - thin as a rake, angina, anxiety, depression, feeling cold allthe time, exhaustion, itching…etc etc both hypo and hyper symptoms in abundance.

TSH110 profile image
TSH110 in reply to Mollyfan

There’s this one:

ahajournals.org/doi/full/10...

And this one

ncbi.nlm.nih.gov/pmc/articl...

And this one, navigate down the hypothyroidism - it lists a shed load of heart abnormalities:

academic.oup.com/europace/a...

Musicmonkey profile image
Musicmonkey in reply to Mollyfan

The only time I get the odd palpitation is when my dose of T3 is due. I take 10mcg at 7am, 2pm and 10pm.

nightingale-56 profile image
nightingale-56 in reply to humanbean

I had Sinus Tachycardia before I was treated with Levothyroxine, but once treated (19 years after sub-total for Graves) this vanished and has not been evident since. Now on NDT, other things have fallen into better places.

helvella profile image
helvellaAdministratorThyroid UK

I wish I had a paper to submit. :-)

It reads extremely well as an intro/summary of intent.

Musicmonkey profile image
Musicmonkey

Thank you diogenes always giving us hope with new scientific articles.

TaraJR profile image
TaraJR

linda96

wantie002 profile image
wantie002

Where will we find the articles this refers to?

diogenes profile image
diogenesRemembering in reply to wantie002

This is all there is at the moment, until the relevant papers get gathered together under this topic.

Not what you're looking for?

You may also like...

A detailed discussion on relationship between cardiac and thyroid function

article is part of the Research Topic Thyroid Hormones and Cardiac Arrhythmia View...

Thyroid Hormones and Blood Sugar Linked to Major Depressive Disorder Severity

distort, pervert the research and do things like: 🔸 Infer that without thyroid hormones, blood...

New paper linking mineral uptake and autoimmune thyroiditis.

of the Research Topic Novel Treatment Strategies for Thyroid Autoimmunity and Thyroid...

Lowered Risk For Thyroid Cancer Linked To Chamomile Tea Consumption

develop the disease. In a study involving 113 patients with thyroid cancers, researchers examined...

Hypothyroid links to mental health?

question about hypothyroid and its links to mental health. I have been diagnosed with hypothyroid...