I was surprised to see no mention of B Vit's for Hypo's?
Blue Horizon gene results came with this advice... - Thyroid UK
Blue Horizon gene results came with this advice...? No mention of B Vit's for hypo's
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TiggerMe
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This came with Blue Horizon results? That’s… new.
Not enamoured with that first recommendation about iodine! And I love how they think getting a good night’s sleep is a simple matter of choosing to get one. Bloody hell, I wish. 
It says not for Hashi’s though. If not autoimmune then the most likely cause is low iodine levels, then you’d need to top up.
Something I've picked up along the way.... "Since levothyroxine already contains iodine, you do not need to take additional iodine to treat hypothyroidism"
Though they give us Hashi sufferers the same Levo? 😕
I assume iodine is rather more useful for the thyroid strugglers (non Hashi) rather than the treated?
So, most people are blissfully unaware of their need until it's too late 🙄 they say your thyroid is likely 90% dead by the time you are diagnosed
At least us in the know who are passing on dodgy genes can guide our poor kids 🙃
Thing is though, you can’t always tell if it’s autoimmune or not. Not everyone with Hashimoto’s has antibodies in their blood. And a lot of GPs won’t send you for what they might see as a fairly pointless ultrasound test to confirm.
So it’s not quite as simple as that.
Also—the cause of hypothyroidism might be pituitary dysfunction. That’s not about iodine deficiency either.
My bed partner is working on exhausting my adrenals further by doing chainsaw impressions at random intervals 😱then insists it's me disturbing him when my shocked system needs a wee!!!!😩 .... spare bed beckons 😴
Spare bed for him, I hope. 😂
Made up with fresh sheets and a super plump duvet... It'll be mine all mine 😉
helvellaAdministratorThyroid UK
Except:
B Complex particularly B1 & B6
At top of middle page! 
B complex
The middle section is for hyperthyroidism, not hypothyroidism.
You are absolutely right!
Sorry - it is so horribly designed, having started working my way through I then missed the header.
Like most such lists - trite, simplistic and not much use. 
Eeyore,
That’s because although Vit B12 is an extremely essential vitamin, it is not directly implicated with the making of thyroid hormone.
It’s association is more through depletion when gut health suffers as a result of malabsorption caused by inadequate thyroid hormones levels. Also deficiencies may produce similar symptoms as those in hypothyroidism .
I thought the test was extremely informative and explained many of my previous symptoms, giving me better understanding of my thyroid inadequacies. I would highly recommend.
What were your genetic impairments?
I’m sure the test itself was good but I think it’s odd this “advice” this was packaged up with the result. B12 might not be part of thyroid hormone production but it takes no time at all to get depleted when you’re under-replaced (or unmedicated altogether because a GP is holding you hostage to a TSH rising over 10).
All kinds of wonky 😏
Gene test result
No doubt you will be looking for more information about all of these, but I am a bit surprised that COMT GG is shown green, when ideally we would all like to be AG, 'normal' speed clearance. I am slow COMT, AA, and have improved hugely with magnesium (although I actually did my gene testing a year or more after getting the benefit, it just explained why that might have been the case for me). You may find this interesting seekinghealth.com/collectio...
Thanks Bookish, I'm having a bit of a foggy week at the moment so I'm holding off analysing the results and asking questions until I'm back up to speed.... thanks for the link 🤗
My COMT GG seems to function well enough as I need to take a reasonable dose of HRT to keep my levels up
Reassuringly my daughter's is a lot less wonky 😅
Yes, take your time to think about it all. But that sort of makes my point - if you weren't clearing oestrogens so fast, you might not need the HRT. I am quite the opposite - can't break down and get rid of the stuff and have reacted badly to any kind of extra hormone since first trying birth control. The mid point would be a happier place to be! Best wishes
It is all fascinating isn't it... can I ask did you share your results with your Endo or GP? I've done it for my own and daughters' interest but don't know if I should share or not...😶
I did mine for my own sanity, after my rheum refused to do the additional B12/folate testing that I thought might give me some answers for myself and my mum. Not just the genetic, as of course that is only having a theoretical effect, but also a hepatic function test to see how well I was actually clearing things (not terribly well). I'd never heard of COMT but it made so much sense when my results came back. So I am doing what I can to improve all of it. From time to time I have mentioned it but got very little interest, although more recently (post-graphs!) I have been referred for NHS genetic testing and my new GP at least didn't glaze over and had heard of COMT. So I suppose it depends on whether they already think you are losing the plot, as mine did at the time, and how well you feel able to cope with that (which I didn't). I was just glad to find that I wasn't completely misguided and that I could do things with diet and supplements to make myself feel a whole lot better. (Don't have an endo as yet.)
Green means fine
Yellow means possibly slight impairment
I'm thinking it's the red TRHR which I'm wondering most about... the others are really just confirming what I already suspected 🤔
Grand finale 💥
Gene test results end
The test itself is fascinating. You’ve got me wondering if I should do it. Heck, both sets of the genetic tests BH do. It would be nice to know if there was a reason I’ve struggled all my life.
Worried that I wouldn’t have the concentration to interpret it properly though.
On sale at the moment....If you have tested with them before you will have earned some pathology points which saves a little more...
There is a triple female pack... I did wonder but thought it's likely only going to raise more questions 😶
As with all things it often only gives you a possible leaning rather than a definitive answer... they always cover themselves with something like "just because it looks wonky doesn't necessarily mean it's the culprit or will fail"
Sometimes I think testing is a bit like reading your horoscope.... you can make it fit if it suits you 🙃
Pleased I got my daughter to do one... though it's a bit crystal ball gazing 🤷♀️
Of course, if the Endo thinks it's of value I shall be delighted, and it would be well worth the cost!!
I thought B12 (balanced B vit's) are essential in the conversion of T4 to T3?
Eeyore100,
Your results are very similar to my own and I suspect to many others on the forum were they to have their thyroid genetic profile completed. This signifies just how ill equipped conventional medicine is in attending to our thyroid and adrenal needs, and how inadequate Levothyroxine is for so many.
I guess it could be said that all vits and nutrients are indirectly implicated in healthy thyroid physiology and there are some B vits whose essentiality is of more importance than Vit B12 but I can’t remember which. It's usually the micro nutrients such as iodine, zinc, selenium, copper, Vit A, etc, and of course iron that are mentioned.
That is interesting to know, thank you.
I have just read through your bio and you have certainly walked the walk 😕 good to know you are taming the beast 🙏
You have been very thorough with your research have you any experience of the Organic Acids Test? Hidden found it very useful
Yes, I did the Great Plains Lab several years back which is supposedly the most comprehensive.
I'm thinking this is my next step in the journey, to understand where I'm at and move forward on a more holistic level
Eeyore100,
I would recommend having a practitioner to help interpret the results as these tests are expensive and need scrutinising from all angles.
If you get a reply for BH, advise the genetic test is great but the list of nutrients for hypos is not only incomplete (regarding Vit B's that you have mentioned) but misleading as to state ‘Iodine is not recommended for Hashimotos’ indicates the rest is recommended for supplementing.
All should be tested before supplementation and some would argue there is even a place for iodine supplementation in an iodine deficient but selenium replete Hashi sufferer, and tyrosine isn’t recommended for people medicating thyroid hormone replacement meds anyway.
They need to remove the list or add something like 'This is a list of thyroid hormone components and not a suggested list for supplementation'.
Edited to tag BlueHorizonMedicals
Yes Hidden said the same, I'm due a windfall next year so will for once invest a little in myself 😏
Eeyore100,
There is also a brand new test coming out that evaluates genetics implicated in the mitochondria. I always thought I had ‘adrenal fatigue’ as want for a better diagnosis. Thyroid genetics have explained a pre-life before NDT of constant cold and tiredness (many have been there!) but even with great hormones/vits/iron labs, great gut microbiome and methylation issues catered for, I still have mouth issues and can’t maintain stamina, feeling drunk after intensive exercise.
This health thing has become a bit hobby-like trying to fathom what is going on because no one else is either knowledgable enough or bothered.
Ooh.. tell me more when you find out 🙏, I am the same with post exertional malaise as someone labelled me 🙄I've been taking adrenals for a month now, I've yet to try another little jog as it generally knocks me out for 2 days 😕... I really must give it a try now the weather has turned
You realise just how backward our health service is, they like you to be acutely dysfunctional before they treat you, rather than nipping things in the bud early or giving guidance!
Like you say we are the only ones with a vested interest in our own health really....
so, game on 💃
in reply to TiggerMe
I'm just jumping on the 'post exertional malaise' bus! I used to run to manage my OCD, even managed a half marathon. Now I can't even run round the block. 😔
TiggerMe in reply to
Oh, that is hard to take... I wouldn't call me a runner, but I had completed the couch to 5k just before the world went mad and made myself jog 3 times a week.... then had the first covid jab and that was the end of that!
Never really enjoyed it but wish I could at least get back to that level, seems I'm ok if I stay in first gear 😕
Perhaps tomorrow I shall give 2nd gear a go and see if the addition of adrenals has made any difference? Just don't really want the crash though 🙄
I wonder if walking with wrist and ankle weights might be an idea?
in reply to TiggerMe
I never really enjoyed running either ... mostly I enjoyed stopping once I'd got home. 😂
Like you; I'm nervous to try stepping up a notch in case it sets me back.
Helvella's Vade Mecum (Fred to me 😏) has a brilliant breakdown of gene traits
Hi Eeyore, we're grateful for the feedback, thank you. With your permission only, I'd be happy to pass your comments onto Kate who runs the genetics reports. Please feel free to email me at paul@bluehorizonbloodtests.co.uk
Hi Paul, yes happy for you to feedback to Kate, other's have made some useful comments and they are far more knowledgeable, hence me seeking their opinions
Good to know you are interested 😉
Kate might find this link useful... thyroiduk.org/role-of-vitam...
thanks for sharing all this info so generously it’s enabled me to sit with my ancestry downloaded DNA open and check through my alleles. Much appreciated 🦋💚🦋
You are very welcome 🤗 the sense of kinship, all trying to help each other along the way is one of the many wonderful things about this forum, there is so much learnt often from just a little comment and shared win or setback.
Most days there is a lightbulb moment and sometimes I can even remember it the next day🤣
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