Good evening
I’m currently on T4/T3 combined therapy, 4 weeks on T3, on 10mg once per day. Don’t feel massively different, brain fog has lifted a little. Just feel like I may need an increase in my dosage, when I’ve read other peoples posts they seem to be on a much higher doseage. Is 10mg a dose that you’d barely notice? Or is a starter dose? Does it take over a month to get its self into your system? Think I was hoping for a minor miracle when I took the drug
Bollie. It took me 2 years of slowly adjusting levo and lio doses one at a time to find doses and dosing times I'm happy with. Some folks only need a little lio. I started on 50mcg levo and 20mcg levo but my total daily doses are now 100mcg levo and 7.5mcg lio. It is very individual.
Bollieforme
I'm like Lalatoot, took me years to find the right combination, was up to 31.25mcg T3 at one point, now settled on 12.5mcg with 107mcg Levo.
Some people find they feel a difference quickly, if I make a dose change it takes about 10 weeks altogether for my levels to completely settle.
Probably not what you really want to hear and I expect your endo doesn't understand that it can take many months of very gradual tweaking, one hormone at a time, to find the right combination for the patient and that we're all different.
It takes 6 to 8 weeks, or longer, for a new dose to settle into the system.....you need to be patient I'm afraid.
Occasionally people do experience a "light bulb moment" .....but not all!!
There is no guarantee that you are on the correct dose yet, it can take months to find one's therapeutic dose.
You will need another test 6/8 weeks after the increase that will point the way forward.
You had T4 reduced from 100mcg to 75mcg when you added T3...
We are advised that this is not necessary because when we add T3 it causes FT4 to drop in any case.
Your FT4 was high but I don't suppose the endo understood it would drop with T3 added.
We only change one thing at a time...that way it's easier to monitor the dose and easier on the system
It would be wonderful,if we could take replacement thyroid hormone and experience fast relief like taking paracetamol for a headache.....alas, no!
I need high dose T3-only to function and it took me nearly 3 years to reach my therapeutic dose!
I could easily have given up....but I'm glad I stuck it out!!
The support I had from members here was crucial to my recovery!
I'm almost 77, so age is just a number!
You had lots of helpful advice in your previous post maybe read the replies again.
10mcg is not the lowest starter dose....give it time.
Don't say to your medics that you are not feeling any benefit from T3....they are all too happy to have any excuse to stop prescribing it. Even if you feel no " miracle" right now just say you do feel a slight improvement so that you keep the prescription and see how future tests go.
I guess you're just looking for encouragement...it can be a long, boring journey but absolutely worth sticking it out.
Hope it helps soon.
DippyDame, yes it’s all so individual and I am on T3 only but your post gave me such encouragement about giving the T3 time to settle! I am only on 20 Mcg total tabs and 30 slow release. Not feeling any better yet after 28 days, I started quite low five months ago to get to this point. Can you tell me what dude you are on…YES I know it’s individual. Thank you.
Hi there, I started on thyroxine several years ago after returning from 10 years in the Caribbean on my sail boat when I returned due to my disability getting to bad for me to manage living on a boat I suddenly found myself with just about zero energy which was unusual as I had never suffered from low or no energy, my doctor took blood and I started off with a couple of huge doses of vitamin D "the doctor said the cause may be to my spending 10 years in the sun" which I didn't see any difference then after getting that back to normal I still had no energy so he started me on thyroxine at 50mg once a day in the morning and after several months and more blood tests he raised it to what I am on now at 75 mg but even while I still have no energy my thyroid level is in the normal range, but enough about me I think that starting out on only 10mg is low I doubt that with my eyes I could not even see the tablet when my thyroxine was raised from 50mg to 75mg I could not keep the tablet in my hand it kept falling between my fingers so I got them to change it from one 50mg and one 25mg to just one 75mg which I can keep in my hand without dropping it on the floor, if the amount you are on does not help then tell your doctor at my doctors I can ask simple questions like this via the online prescription orders I think it is better to ask questions via the Internet as it saves an appointment with the doctor which are scarce now a days.
Good luck in getting your level under control and back to normal.
Ps just a quick note do you know that if you are on thyroxine full time you get free prescriptions from now on, only good thing there is to having low levels.
Regards Poppy Ann
I started out taking 75mcg Levothyroxine which I struggled on for about 11 years. I became very unwell in 2018. I had zero energy. I went private to find I am a very poor converter of Levothyroxine T4 and have the faulty DIO2 gene. I was prescribed Liothyronine T3 combined with T4 liquid Levothyroxine. I was on 75mcg liquid Levothyroxine which wasn’t changed and we added 5mcg Liothyronine T3 twice a day 8hrs apart. Oh my goodness what a huge positive outcome for myself. I could now walk and had plenty of energy. I’d piled on over 4st before introducing T3 Liothyronine. Within a year that 4st was gone without me even trying. My metabolic rate was now functioning properly and I was walking more. I’ve not looked back. People say 5mcg twice a day maybe a low dose but for myself it’s a perfect dose. My T3 bloods prior to being prescribed Liothyronine T3 was only 8% through the range due to poor conversion from T4 Levothyroxine. Now it’s 60% through the range. I feel at my optimal level. If my levels go over medicated I lose energy and feel very heavy. It’s trying to find your own personal optimal point and sticking with it. I joined a gym and started exercising before the pandemic, I found that I needed to increase to 3 doses of 5mcg a day 8hrs apart. Now that I don’t go the gym I’ve reduced back to 5mcg twice a day. For myself it seems to be energy output versus tablet/dose input. Too much can feel like under medicated, it zaps your energy when over levels I find.
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