An old paper describing the effect of a DI01 mutation on FT4 FT3 and rT3 levels in humans

[diogenes]

It's rather an old post but the paper describes what effect the DI01 mutation has on thyroid hormone levels and goes a little into combination therapy. Useful for those having the mutation to educate their GP when treatment is needed .

J Clin Endocrin Metab.

First published ahead of print May 20, 2008 as doi:10.1210/jc.2008-0397

A Common variation in Deiodinase 1 gene DIO1is associated with the relative levels of free thyroxine and triidothyronine.

Vijay Panicker, Christie Cluet, Beverley Shields, Anna Murray. Colin Dayan, Bjay Vaiya et al

[diogenes Remembering]

Sorry, I've already posted this. The flood of papers is getting rather difficult to manage and comment on.

[TaraJR in reply to diogenes]

Don't apologise - it's good to have them coming! For new members, and those of us who've forgotten about certain papers! Thank you so much for all the work you do, and the amount you do on HU to keep us abreast of what really helps.

[Nat107]

Thank you Diogenes, please don’t apologise as lots maybe have Not seen it, me for one, which is a very important read for me so thanks again

[JGBH]

Thank you again for all your efforts, so appreciated by all of us. So kind.