Just thought it interesting

[Polo22]

medscape.com/viewarticle/97...

if it works

[SlowDragon Administrator]

Article discussing

Lecture by Antonio Bianca this May

Debate Continues on Combination Therapy for Hypothyroidism

May 20, 2022

It's "critically important" for clinicians to recognize that not all patients with hypothyroidism are fully treated with levothyroxine (LT4) and some may need combination treatment with triiodothyronine (LT3) despite normal levels of thyroid stimulating hormone (TSH), according to thyroid expert Antonio C. Bianco, MD, PhD.

[Polo22 in reply to SlowDragon]

Did I repeat post this? 😊

[SlowDragon Administrator in reply to Polo22]

No

See all your posts on your profile page

healthunlocked.com/user/Pol...

[Polo22 in reply to SlowDragon]

Ok thanks

[RedApple Administrator in reply to Polo22]

No you didn't repeat post on this forum. But neither did you tell us what your link is about, which is what we ask members to do when posting links to things they think are interesting. That's why SlowDragon has commented.

[RedApple Administrator in reply to RedApple]

Forum posting guideline

17. If you post a link, please at least explain briefly what people can expect to find if they follow the link. Links without such an introduction/explanation may be deleted.

healthunlocked.com/thyroidu...

[Polo22 in reply to RedApple]

Oh I see, thanks was thinking the brain was foggy again

[humanbean]

From the article :

"Levothyroxine is so long-acting it's easy to give. Often patients have to take LT3 more than once a day on an empty stomach. There's no combination pill as of now."

No, no, NO! I don't want a doctor telling me what proportion of T4 to T3 I'm allowed! I want to take the proportion that is right for me, not what a manufacturer wants to make.

[greygoose in reply to humanbean]

They already do. It's 100 mcg T4 and 20 mcg T3. It's called Euthyral in France. Don't know if you can get it in the UK. But it wasn't nearly enough T3 for me, and far too much T4.

[humanbean]

From the article :

Tessnow and Bianco both noted that most of the studies that have failed to show a benefit of combination LT4+LT3 treatment have included overall populations with hypothyroidism rather than focusing just on those who remain asymptomatic with LT4.

"It is possible that those individuals most likely to benefit from combination therapy may not yet have been included in trials in sufficient numbers in order to provide adequate power for detecting a response," Bianco said.

This is exactly what diogenes and his team have been saying for years. Bianco says this as if it is his realisation.

[Gingernut44 in reply to humanbean]

Did it really say focussing on those who are asymptomatic with LT4 ?

[humanbean in reply to Gingernut44]

Well spotted. And yes, it did say that on page 2 of the article linked by the OP.

[Gingernut44 in reply to humanbean]

Well, there’s no hope then if he can’t even get the terminology right 😱