This paper shows that quality of life in so-called well treated hypothyroidism is dependent on TSH values even in the higher reachs of the healthy TSH range. Now our group can explain this easily. The TSH range for controlled hypothyroidism is NOT the healthy range, but a TSH range much lower than this with little overlap. This is because without a thyroid making some of the T3 needed for health, the larger amount of T4 that must be taken to make up for this partially suppresses TSH. No wonder patients in the higher area of the reference range have a poorer QoL. They simply aren't being well controlled. But the authors are oblivious to this. It's a good example of how making the healthy TSH range the determinant of good treatment misleads the medics who write paper like this. It is an excellent example of how far the discipline has to travel to realise its ignorance of these facts.
Endocrine (2021) 72:190–197doi.org/10.1007/s12020-020-...
Correlation between TSH levels and quality of life among subjects with well controlled hypothyroidism
Mara Moron-Diaz, Pedro Saavedra, Maria P Alberiche-Ruano, Carlos Rodriguez-Perez et at