New insights on the effects of endocrine-disrupting chemicals on children

[helvella]

The possible impact of numerous substances on the endocrine system has long been discussed. But all too often dismissed. We have seen some specific substances hit headlines, such as Bisphenol-A (BPA), and widely claimed to have been removed. But no-one seems to question the other bisphenols - AF, B, BP, C, C2, E, F. G, M, S. P, PH, TMC, Z, etc.

Though this paper refers to children, we have all grown up with many of these substances around us. We were affected in these ways when we were children. How many of us were affected by EDCs - sometimes resulting in our current states of health?

J Pediatr (Rio J). 2021 Dec 15;S0021-7557(21)00163-7.

doi: 10.1016/j.jped.2021.11.003. Online ahead of print.

New insights on the effects of endocrine-disrupting chemicals on children

Barbara Predieri 1 , Crésio A D Alves 2 , Lorenzo Iughetti 3

Affiliations

• PMID: 34921754

• DOI: 10.1016/j.jped.2021.11.003

Abstract

Objective: Endocrine disrupting chemicals (EDCs) are present in many areas and materials of the common life, and exposure to these chemicals can occur from products to personal care, from air and food. This review aims to summarize the more recent epidemiological findings for the impact of EDCs on endocrine system health in children, including effects in growth, metabolism, sexual development, and reproduction.

Sources: The MEDLINE database (PubMed) was searched on August 24th, 2021, filtering for EDCs, endocrine disruptors, children, and humans.

Summary of the findings: Intrauterine exposure of EDCs can have transgenerational effects, thus laying the foundation for disease in later life. The dose-response relationship may not always be predictable as even low-level exposures that may occur in everyday life can have significant effects on a susceptible individual. Although individual compounds have been studied in detail, the effects of a combination of these chemicals are yet to be studied to understand the real-life situation where human beings are exposed to a "cocktail effect" of these EDCs. Epidemiological studies in humans suggest EDCs' effects on prenatal growth, thyroid function, glucose metabolism, obesity, puberty, and fertility mainly through epigenetic mechanisms.

Conclusions: EDCs cause adverse effects in animals, and their effects on human health are now known and irrefutable. Because people are typically exposed to multiple endocrine disruptors, assessing public health effects is difficult. Legislation to ban EDCs and protect especially pregnant women and young children is required and needs to be revised and adjusted to new developments on a regular basis.

Keywords: Adolescents; Children; Endocrine disruptors.

pubmed.ncbi.nlm.nih.gov/349...

Open Access so freely accessible here:

sciencedirect.com/science/a...

[shaws Administrator]

Thanks for posting helvella this interesting and informative post,

[Swissgirl]

Thank you Helvella. Izabella Wentz ( thyroid pharmacist) wrote an interesting article on this on her website: thyroidpharmacist.com/artic...

There are so many hidden ‘nastys’ all around us, no wonder there are so many of of us with thyroid problems. The air we breath, the food we eat, the things we drink, beauty products, cosmetics, clothing dyes…the list is endless and we can only do so much ourselves. This is a particular area of interest of mine as apart from being diagnosed with Hashis 10 yrs ago, I have also been diagnosed with histamine intolerance and am in the process of being diagnosed with potential Mast Cell Activation Disorder.

[Hidden]

One of the Big ones that scrapes under the Radar is Weedkillers Glyphosates ie Round-up for one is a massive EDC they had to years back had to keep reclassify "Safe" by who ever kept reclassifying "Safe Levels" as was increasing in the Environment ten fold year on year so there has/is a lot of conclusion between Chemical companies and .gov bodies!

In Males causes Endocrine disruption Corrupts Testosterone so it no longer works for you but against you as testosterone is a weak hormone.

Pretty sure it's where i got my Pituitary tumour from as they found in testing it caused them

Used to work with the crap it was said all safe/bio degradable blah blah yet had to remove Bio degradable after the French gov kicked up a stink as in testing it's still killing everything in the soil one reason now we need so much fertiliser to grow crops as soils barren.

Non Hodgkin's Lymphoma and many other illnesses and cancers been a huge case in USA over it.

All our rivers are poisoned by it and other chemicals there is charts somewhere showing run off's and entering the sea with levels and amounts of! East Anglia is bad.

It effects fish with breeding and marine life not to mention algal/weed blooms!

Places like South America where spraying wholesale it's causing massive health issues.Cancers.Birth defects and so much more The Lid is being firmly shut on matters there!

It's in our water/air what we eat and all sorts plus kills bees and birds.

Watch a you tube vid about it long time back.World according to monsanto probably vanished by now? They show you lot's on it and dangers one being cell division.

Yet because "Big Business" it's fine keep poisoning us. plus it's one of the things that will cause global warming as the soil no longer lives as it should

[LindaC]

More than likely contributing to the mammoth obesity crisis!? 👽😱