T3 and levo dose adjustment

[JBLOVELL]

Please advise on any dosing adjustments I should make please. Below are my blood results. I have adjusted my meds before the last test down to 125mg of levothyroxine from 150mg and I’m currently on 12.5 t3 split into 2 doses. I still get overheated and have palpitations but this could be due to my blood pressure and another medication called venlafaxine, that causes sweating. My mood is low. Thank you .

[SeasideSusie Remembering]

JBLOVELL

When did you take our last doses of Levo and T3 before the test? Last dose of Levo should be 24 hours before, last dose of T3 should be 8-12 hours before.

How long have you been on your current doses?

[JBLOVELL in reply to SeasideSusie]

Levo was 24 hours and t3 was 10 hours. I’ve been on this dose 6/7 weeks.

[SeasideSusie Remembering in reply to JBLOVELL]

JBLOVELL

So your FT4 might still be too high for you, it's 97% through range (we are all different where we need this when on combination replacement hormone). Your FT3 is only 35% through range and when on T3 we generally need this higher in range.

If those were my results I would reduce Levo by 12.5mcg, wait a week or two then increase T3 by 6.25mcg (total 18.75mcg assuming you have 25mcg tablets). Retest 6-8 weeks after last dose change.

[JBLOVELL]

I didn’t realise that t4 being too high for me could cause this. I thought it was only t3. I’m learning so much. Thank you .

[waveylines]

A lovely old school endo once told me that so long as your thyroid hormobes are i. Range you can do no harm. Wise words. You did right to reduced and I think seaside Suzie's advice for the next step of your meds is spot on. Its all about tweaking now to get the optimal dose for you.