Thyroid cancer incidence in children and adolescents

[holyshedballs]

From The Lancet

thelancet.com/journals/land...

Thyroid cancer incidence in children and adolescents

Livia Lamartina Sophie Leboulleux Martin Schlumberger

Published:January 19, 2021DOI:doi.org/10.1016/S2213-8587(...

Clinically detected thyroid cancer is rare in children, with one to three cases per 1 million children per year. The disease—a papillary carcinoma in most cases—is frequently more extensive at diagnosis in children than in adults, particularly in children aged younger than 10 years who often have large thyroid tumours with lymph node and lung metastases. 1

The overall prognosis is favourable even in cases of metastatic disease, but the treatment burden can be substantial, and thyroid cancer related deaths that are extremely rare during childhood and adolescence have been reported several decades after initial diagnosis, at an adult age. 2

The incidence of clinical thyroid cancer increases with age, and the extent of disease is usually less in adolescents and young adults, who have excellent long-term prognoses.

1.

Hay ID Johnson TR Kaggal S et al.

Papillary thyroid carcinoma (PTC) in children and adults: comparison of initial presentation and long-term postoperative outcome in 4432 patients consecutively treated at the Mayo Clinic during eight decades (1936–2015).

World J Surg. 2018; 42: 329-342

2.

Schlumberger M De Vathaire F Travagli JP et al.

Differentiated thyroid carcinoma in childhood: long term follow-up of 72 patients.

J Clin Endocrinol Metab. 1987; 65: 1088-1094

[helvella Administrator Thyroid UK]

holyshedballs - thank you.