Calcitonin hormone and the thyroid.: A recent... - Thyroid UK

Thyroid UK

140,930 members166,052 posts

Calcitonin hormone and the thyroid.

Read58 profile image
3 Replies

A recent article released by the British Heart Foundation ( apparently a game changer) links lack of the hormone calcitonin with heart problems, including atrial fibrillation, strokes, etc. If Calcitonin is produced by a functioning thyroid , does this make us more susceptible . Tried reading up on mr google but still no clearer (to me anyway ).

Written by
Read58 profile image
Read58
To view profiles and participate in discussions please or .
Read more about...
3 Replies
Read58 profile image
Read58

Thanks Scrumbler, thats excellent. Reassuring to know its not just produced in the thyroid. Thanks for taking the time to reply.

buddy99 profile image
buddy99

Have you tried pubmed? I found a lot of articles (did not read, though).

Poniesrfun profile image
Poniesrfun

This was of great interest to me as I have medullary thyroid cancer and the marker tested for recurrence is calcitonin. It was challenging to find good discussions. But what I did find is that the “calcitonin” produced by cardiac cells as discussed in the article is not the same as the bone-modulating calcitonin produced by C-cells in the thyroid. Thyroid calcitonin is “a 32 amino acid polypeptide hormone” while the cardiac “calcitonin” is caused by “Alternative splicing of the gene coding for calcitonin produces a distantly related peptide of 37 amino acids, called calcitonin gene-related peptide (CGRP), beta type. ”. Despite the similar name very different proteins and functions.

en.wikipedia.org/wiki/Amyli...

As the study abstract (the complete study is behind a paywall) does not make this distinction - in fact it conflates cardiac calcitonin gene-related peptide with thyroidal calcitonin, it’s no wonder the article author makes the same error - a disservice to thyroid patients.

Not what you're looking for?

You may also like...

Calcitonin

I read where calcitonin is harmful, please advise?
Diana58 profile image

Calcitonin - evidence of under treated hypothyroidism ?

For a few years now I have noticed, as has my dentist, that I have a lot of dental plaque. Really a...

Thyroid Hormone and Heart Disease

An excerpt:- Hunt Study (in April 2008)Shows Thyroid Prevents Heart Attacks by Jeffrey Dach MD In...
shaws profile image
Administrator

Calcitonin , is this the main cause for lingering symptoms in spite of taking levo?

I've done some research on my own and still fail to answer this particular question: why is...

Calcitonin

I've recently read a bit about this and it is produced in humans in the thyroid gland. As mine has...
Summer64 profile image

Moderation team

See all
RedApple profile image
RedAppleAdministrator
PurpleNails profile image
PurpleNailsAdministrator
helvella profile image
helvellaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.