This paper examines the proven value of the herb Prunella vulgaris against Hashimoto's thyroiditis antibodies. Traditional medicine can work if it has been shown to be empirically effective in the past.
Front. Endocrinol., 16 November 2020 | doi.org/10.3389/fendo.2020....
Innate Immune-Modulatory Activity of Prunella vulgaris in Thyrocytes Functions as a Potential Mechanism for Treating Hashimoto’s Thyroiditis
Fei Chen Akira Kawashima, Yuqian Luo, Mitsuo Kiriy and Koichi Suzuki
Department of Clinical Laboratory Science, Faculty of Medical Technology, Teikyo University, Tokyo, Japan
Department of Thyroid Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China
Department of Laboratory Medicine, Nanjing Drum Tower Hospital and Jiangsu Key Laboratory for Molecular Medicine, Nanjing University Medical School, Nanjing, China
Prunella vulgaris (PV), a perennial herb, has been used to treat thyroid diseases in China for over 2,000 years. In particular, its therapeutic effect has been described for Hashimoto’s thyroiditis, including reducing titers of autoantibodies against thyroid peroxidase and thyroglobulin and T helper 17 (Th17) cells. However, the underlying mechanism for how PV exerts such effects has not been investigated. We examined the effects of PV on innate immune activation, which is thought to be one of the triggers for the development of autoimmune diseases, including Hashimoto’s thyroiditis.