Levothyroxine night time

[Katrina999666]

Would there be any problem taking my dose of Levothyroxine at night prior to bed? Thanks

[soppysokes]

as long as you stick to a regular timing and a 2 hour gap since food it not particularly important what time its taken. best to try and see if it suits you, many take it at night, or during night

[Katrina999666 in reply to soppysokes]

Thanks for replying

[helvella Administrator]

It is often suggested that bed-time dosing results in slightly better absorption. It also seems slightly closer to the pattern healthy people have.

I have always taken my levothyroxine at bed-time.

For that reason, I cannot compare with taking in the morning.

Before diagnosis, my sleep was badly disturbed. Typically, I would fall asleep fairly easily. Then wake up after something like half an hour to two hours. Once woken I'd be unable to get back to sleep - often till dawn, or at all.

Once I started on levothyroxine, my sleep slowly improved. By the time I was taking an adequate dose, bad nights were unusual - just an occasional night where I might wake up for a while. Now, after years, I sleep very easily and deeply and rarely wake at all. If I do, I get back to sleep quickly.

We have some who prefer it; we have others who prefer other times. See our poll:

healthunlocked.com/thyroidu...

Some papers which discuss taking levothyroxine at different times - such as bed-time.

Levothyroxine Replacement and Ramadan Fasting

pubmed.ncbi.nlm.nih.gov/237...

Effect of L-Thyroxine Administration Before Breakfast vs at Bedtime on Hypothyroidism: A Meta-Analysis

pubmed.ncbi.nlm.nih.gov/320...

Morning vs. Bedtime Levothyroxine Administration: What Is the Ideal Choice for Children?

pubmed.ncbi.nlm.nih.gov/303...

A Crossover Study Evaluating Effect of Timing of Levothyroxine on Thyroid Hormone Status in Patients of Hypothyroidism

pubmed.ncbi.nlm.nih.gov/313...

Effect of Timing of Levothyroxine Administration on the Treatment of Hypothyroidism: A Three-Period Crossover Randomized Study

pubmed.ncbi.nlm.nih.gov/300...

Alternative Schedules of Levothyroxine Administration

pubmed.ncbi.nlm.nih.gov/256...

Thyroid Diseases and Ramadan

pubmed.ncbi.nlm.nih.gov/228...

Pharmacotherapy: Hypothyroidism-Should Levothyroxine Be Taken at Bedtime?

pubmed.ncbi.nlm.nih.gov/213...

Effects of Evening vs Morning Levothyroxine Intake: A Randomized Double-Blind Crossover Trial

pubmed.ncbi.nlm.nih.gov/211...

Timing of Levothyroxine Administration Affects Serum Thyrotropin Concentration

pubmed.ncbi.nlm.nih.gov/195...

Effects of Evening vs Morning Thyroxine Ingestion on Serum Thyroid Hormone Profiles in Hypothyroid Patients

pubmed.ncbi.nlm.nih.gov/172...

[Katrina999666 in reply to helvella]

Thank you I will have a read at these links

[fuchsia-pink]

Don't forget to move to a morning dose the day before a blood test so that you leave 24 hours - and have the early blood draw that is recommended here

[Ellie-Louise in reply to fuchsia-pink]

I don’t, I just don’t take it the night before. Why mess up your routine!

[fuchsia-pink in reply to Ellie-Louise]

Because you need to leave 24 hours or you will get a false result ... I'd rather "mess up my routine" very occasionally and get an accurate blood result, but we're all different!

[Ellie-Louise in reply to fuchsia-pink]

That’s why I forget the night befores. That way I have a clear 36 hours, it makes no difference to me.

If you suddenly change to a morning then you are messing up.

[Katrina999666]

I will make a note of that thanks