Autoimmne thyroiditis and vitamin D deficiency ... - Thyroid UK

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Autoimmne thyroiditis and vitamin D deficiency are strongly linked

diogenes profile image
diogenesRemembering
20 Replies

This article (easily downloadable) demonstrates what patients on this forum well know: the strong link between Hashimoto's and Vitamin D.

Front. Endocrinol., 14 February 2020 | doi.org/10.3389/fendo.2020....

Correlation Between Hashimoto's Thyroiditis–Related Thyroid Hormone Levels and 25-Hydroxyvitamin D

Guanqun Chao*, Yue Zhu and Lizheng Fang*

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diogenes profile image
diogenes
Remembering
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jgelliss profile image
jgelliss

This is something that I now know too well about now. This information over 25 years ago was very little known about if any . I ended up needing unfortunately TT as I'm afraid many others too . Thank You So Much For Sharing Diogenes . Great and Very Useful Information .

humanbean profile image
humanbean

I find it odd that the research found a strong correlation between being male and having Hashi's. It doesn't mention "male" just once, but several times.

In the Results section :

Multiple regression analysis showed that HT was statistically significantly correlated with being male, body mass index (BMI), waist circumference, and thyroid-stimulating hormone (TSH).

Further down : General Data and Correlation Analysis

The mean age was 48.95 ± 9.06 years old, and 60.1% were male.

shaws profile image
shawsAdministrator in reply to humanbean

Maybe it was the researcher who was researching why he had unpleasant symptoms then found out about hashi's and assumed he may be the only person to develop this condition :)

Baobabs profile image
Baobabs

Yes seems like a relevant study for once. Appears to be a significant sample also. Strange that the Chinese should be looking at this correlation? I'd be interested to know what your opinion is diogenes on the sampling and origin of this study, you being a researcher and all that.

diogenes profile image
diogenesRemembering in reply to Baobabs

Probably it is more male-oriented because in China, boys (males) are valued over daughters (thus the huge male preponderance in China owing to the one-child rule only recently lifted). China has 1/3 of the world population so they can reach lots of subjects for any study. Chinese scientists are busy people - they want to shine on the scientific world stage. In some ways they are not hidebound by Western scientific beliefs - though this can impinge on the soundness of their work. In this case I think they have done something useful.

Baobabs profile image
Baobabs in reply to diogenes

I really appreciate your response as you have a professional perspective most of us don’t. I just had a good feel about it and for most could understand it.

shaws profile image
shawsAdministrator

Thank you diogenes, yet again, for giving us good and worthwhile information.

Baobabs profile image
Baobabs

I also meant to say that the correlation is no surprise and I would guess low levels of D3 is correlated to several diseases.

Marz profile image
Marz in reply to Baobabs

grassrootshealth.net

Within the above website there is a Prevention chart indicating where levels are good to prevent several illnesses - including some cancers.

Moons ago helvella posted a piece of research done in Crete - about some people being unable to metabolise VitD.

SlowDragon profile image
SlowDragonAdministrator

More research links saying exactly same thing .....

Yet so many people with hashimoto’s struggle to get GP or endocrinologist to test vitamin D .....or B12, folate and ferritin either

ncbi.nlm.nih.gov/pubmed/286...

Vitamin D deficiency is frequent in Hashimoto's thyroiditis and treatment of patients with this condition with Vitamin D may slow down the course of development of hypothyroidism and also decrease cardiovascular risks in these patients. Vitamin D measurement and replacement may be critical in these patients.

endocrine-abstracts.org/ea/...

Evidence of a link between increased level of antithyroid antibodies in hypothyroid patients with HT and 25OHD3 deficiency may suggest that this group is particularly prone to the vitamin D deficiency and can benefit from its alignment.

ncbi.nlm.nih.gov/pubmed/300...

ncbi.nlm.nih.gov/pmc/articl...

Our results indicated that patients with hypothyroidism suffered from hypovitaminosis D with hypocalcaemia that is significantly associated with the degree and severity of the hypothyroidism. That encourages the advisability of vit D supplementation and recommends the screening for Vitamin D deficiency and serum calcium levels for all hypothyroid patients.

penny profile image
penny

Dr Coimbra has been working for 20 years with Vitamin D and autoimmune conditions. He thinks that those with autoimmune conditions, such as MS and RA, have a resistance to utilising vitamin D and then need huge doses to overcome this. I assume that this is similar to those of us who have THR.

I have been ‘soapboxing’ for years about the importance of vitamin D and am now beginning to be taken seriously. (Although I have a brother with prostate cancer who assures me that he gets enough vitamin D from his food!)

Since told about the importance of vitamin D by the private doctor who diagnosed my hypothyroidism I have been supplementing 5,000iu per day.

Assasss profile image
Assasss in reply to penny

It’s true about vitamin d and I although live in Greece with lots of sun the majority of people here are deficient, including me

However, my Endo gave me 25000 iu per week and I am concerned about causing other problems perhaps kidney issues

I don’t know just concerned

penny profile image
penny in reply to Assasss

Hi Assasss, I’m not a medic so this is only my opinion. I understand that taking K2-MK7 or K2-MK4 when taking vitamin D directs calcium to the bones and teeth. Vitamin D (not a vitamin) is not in itself toxic but can cause hypercalcemia depositing calcium in soft tissue. Magnesium is needed to utilise the vitamin D. Dr Coimbra stresses that anyone following his protocol must do so under strict medical supervision but then he uses 100,000-250,000iu per day. 25,000iu per week does not sound very much to me. Did your Endo give you any instructions as to K2 and magnesium? I’m not deficient in vitamin D and take 10,000iu per day in the winter.

Assasss profile image
Assasss in reply to penny

Yes she gave me magnesium too

Baobabs profile image
Baobabs in reply to penny

I wonder if there is any research regarding the K2-7 directing calcium to the bones and stopping deposits in the arteries. I take it but my Endo doesn't believe in it and he is well into testing all the necessary vits and minerals optimum for Hashi's and treats Osteoporosis.

penny profile image
penny in reply to Baobabs

That is a good question, Baobabs; I don’t know but will have a search now that you’ve raised it.

Baobabs profile image
Baobabs in reply to penny

I would help but on line teaching at the moment

penny profile image
penny in reply to Baobabs

ncbi.nlm.nih.gov/pmc/articl...

First one that came up.

Baobabs profile image
Baobabs in reply to penny

Just finished reading thanks. I have to take additional calcium supplements to keep mine at the top of the range. We actually need to take a lot in our diets to get the required daily amounts. I do not have a high dose supplement but take vit k2-7 also as it was recommended for the reasons this study states.

penny profile image
penny in reply to Baobabs

There’s a book about vitamin K2. Can’t stop now as sun is shining and digging awaits.

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