Strange simptoms on levo.: I don't know why when... - Thyroid UK

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Strange simptoms on levo.

hipolion profile image
22 Replies

I don't know why when I try to increase the levo dose I get some disturbing symptoms. In the morning after I take my 125 levo I get anxiety(btw 10-11am), don't feel taste and smell, constipated, bloated, aching joints and drowsiness, which alleviates to afternoon. My heart rate goes up too. If I add t3 it doesn't help to much.

If I take 112 levo, I do not have these symptoms but I feel bad(hypo) in the afternoon and I can't sleep. How can I fix these. My endo says they are transient and wants to increase the dose further.

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hipolion profile image
hipolion
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22 Replies
Buddy195 profile image
Buddy195Administrator

My heart rate also rises when I try to increase Levothyroxine. My Endo likewise assured this will pass and recommended 5 days at a lower dose and 2 at 12.5mg higher.

Suggestions on my post yesterday were that higher heart rate might be linked to insufficient ferritin. Have you had your key vitamins checked recently?

hipolion profile image
hipolion in reply to Buddy195

I doubt the rest of the symptoms will go away; lack of taste and smell, aching joints and drowsiness. The more levo I take, the more I swell. Very unpleasant, my endo suggested a small dose of ssri & beta-blocker..

Buddy195 profile image
Buddy195Administrator in reply to hipolion

My achey joints eased when my Levo dose was raised and my gut issues have reduced with a Gluten free diet. I feel more alert with a B12 increase.

The lack of taste & smell seems unusual, but I’m sure someone this forum will have experienced similar!

Lalatoot profile image
Lalatoot

Sit your dose and take 1 am an one pm or bedtime.

hipolion profile image
hipolion in reply to Lalatoot

what to take (at am & pm) ???

Lalatoot profile image
Lalatoot in reply to hipolion

Take half your levo in the morning and half at night.

hipolion profile image
hipolion in reply to Lalatoot

Today I was thinking about it, 100levo +t3 in the morning and 25evo +T3 pm.

Lalatoot profile image
Lalatoot in reply to hipolion

Whatever suits. I take 25mcg levo and 5mcg T3 at 6am, 25mcg levo and 5mcg around 4pm and 10mcg t3 at bedtime.

vocalEK profile image
vocalEK in reply to Lalatoot

You probably intended to type "split your dose", rather than "sit."

Lalatoot profile image
Lalatoot in reply to vocalEK

I did. For some reason when I go to edit post on my computer or phone it doesn't let me proceed! I need to take more care and read what I type before clicking the button!

brucergoldberg profile image
brucergoldberg

I have the same thing. I get massive fatigue upon bumping. I do split my t4 dose as well. 50 at night and 25 daytime with some t3 but just make it 50 and 50

brucergoldberg profile image
brucergoldberg

also taking different doses during the week is not advised. better off finding a middle dose and taking it consistently every day.

Eyes-wide-shut profile image
Eyes-wide-shut

Hi hipolion

I’m sorry to hear about your symptoms. I get all of those too but not all the time. I have Graves and had radioiodine so now am hypo but not due to Hashi. My symptoms come in phases and I think they are due to high Graves antibodies.

I found taking Levo at night better. I alternate between 125 mg and 150 mg. my symptoms only have only improved with a course of IV steroids followed by the introduction of an immunosuppressant. So I’m now taking 1.5 grams mofetil (it’s usually given to transplant patients). My endo has been fantastic but it’s taken a very long time to find her. I don’t know where you are in the country but if near london private message me and I’ll send name of my endo.

I hope that helps and that your symptoms resolve soon. 🙏

cbraffe profile image
cbraffe

I had the same symptoms but it was after testing for vit that my GP put med on vit D supplements and Iron tablets that I felt better. The smell is due to Levo but it something one can live with as long as the heart pounding and achy joints is alleviated. I am alot better thanks to this forum

Darty3 profile image
Darty3

I lost sense of smell when on T4 alone. It returned when I started on T3 as well.

Lora7again profile image
Lora7again in reply to Darty3

I lost my sense of smell and taste when I very ill last year it has now returned now I am in remission from Graves' Disease

Hello, how long have you been taking your meds ?

I find that each day I feel different, usually really tired & sluggish... most days I need a sleep in the afternoon, but that's difficult working full time.

Have you tried taking your meds before you go to bed? I used to take mine in the morning, but felt like I had brain fog... at night, your body's resting & the meds have a chance to get into your system & you feel better in the morning. Also take a multi-vitamin too, it helps to keep your body free from illnesses.

Try not to do much each day, see how you feel, if you feel up to doing something then go ahead. Remember an hour or two at the most.... try to go for a walk or take the dog out. The fresh air will help you too.

Be kind to yourself .... everyone on the meds have a different experience.

Myro profile image
Myro

Changing dose from 112 to 125 is not high change to You but it is for your body. Try to increase every few days with 3 each time. It is like to drink 4 brandy and when being on dose to take just one more.

If You take additional T3 it is same thing, It looks that you convert T4 into T3 correctly but test when tests will be done.

When raising or going down with dose stop when symptoms go away.

Change of every thyroid influencing stuff should be by just a little to give time to body, to adopt. Otherwise it is sad you have allergy or intolerance to medicine or stuff. It is severe in case of Hasshimoto. Our bodies react to same medicine on different way. Even on food.

By Your description I suggest to go on low carbohydrate, low GI diet. Check iodine level too. Do not believe anybody, anything, even yourself. Check, test, prove.

hipolion profile image
hipolion

Thank you all for reply, my endo told me to take it 25mch T3 along with 125levo but I found it is very dificult, my heart doesn't like it. On the other hand, I am no longer tired, no longer sleeping in the afternoon. Gave me some beta-Blck to take.

vocalEK profile image
vocalEK in reply to hipolion

25 mcg of T3 is a very high starting dose. Low and slow is best. Start with 5 mcg. Increase after a week or two by adding another 5 mcg. You can probably work your way up to the full 25 mcg, but not all at once!

jgelliss profile image
jgelliss

It could be possible that you would be a great candidate to split your T4 dose . AM and in the afternoon . I split my T4 dose for a few years now . It works very well for me . You might want to try it and see how that works for you .

hipolion profile image
hipolion in reply to jgelliss

Yep, today I splited(like ndt). 100levo+10T3 in the morning and 25levo+5T3 in the afternoon, seems to work. Maybe not the best ratio(I have to experiment), noon dose makes me a little anxious/jittery and it causes heartburn.

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