Sertraline & Levothyroxine....: Last time I was... - Thyroid UK

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Sertraline & Levothyroxine....

Sarahlouise1980 profile image
5 Replies

Last time I was put on Sertraline it interfered with my Levothyroxine and I needed an increase of 25mcg Levothyroxine to get my levels back to where they should be. Yesterday my doctor put me back on the Sertraline and suggested putting my Levothyroxine dose up 25mcg so that my levels don’t drop again. Is this wise? xx

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Sarahlouise1980 profile image
Sarahlouise1980
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Lalatoot profile image
Lalatoot

Yes. It is well documented that SSRi types of medication affect the action of levothyroxine.

Sarahlouise1980 profile image
Sarahlouise1980 in reply toLalatoot

But increasing before it’s affected my levels?

Lalatoot profile image
Lalatoot in reply toSarahlouise1980

It takes 4 - 8 weeks for any change in levo to become effective depending on the individual. It takes 3 weeks or so for SSRis to get into the system.

Sarahlouise1980 profile image
Sarahlouise1980 in reply toLalatoot

I’m just worried I will become over medicated on the extra Levothyroxine?

Lalatoot profile image
Lalatoot in reply toSarahlouise1980

There's no way of predicting if or when you will need the increase. You need to go by your instinct.

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