Hypothyroidism : Hi, so after a year of being... - Thyroid UK

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Hypothyroidism

EllaRoulette profile image
5 Replies

Hi, so after a year of being subclinical hypothyroid, I now have hypothyroidism. TSH 14, T4 10 and have started thyroxin at 25 mg (started low as im sensitive to medication and have a lot of other conditions like hEDS, POTs, gastroparesis)

My question is, how long does it take to start feeling better, are there any questions I should ask my doctor?

Thank you :)

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EllaRoulette
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MaisieGray profile image
MaisieGray

There is no set period for "feeling better", we are each individual in how we recover, and indeed, will begin taking replacement hormone at different stages of having become unwell due to our dysfunctional thyroid. Unfortunately, starting on too low a dose as you have done, can actually have a negative, rather than a positive, effect. You might assume that the 25 mcg L-thyroxine is topping up the thyroid hormones that your thyroid is managing to make, but in fact, due to the negative feedback mechanisms that are in play between the thyroid, pituitary gland and hypothalamus, it may be just enough to interrupt/reduce exogenous production so that you can have less rather than more, as a result.

EllaRoulette profile image
EllaRoulette in reply to MaisieGray

Thank you! Oh I didn't know that, i'll talk to my gp. thank you

shaws profile image
shawsAdministrator in reply to EllaRoulette

Keep in mind Ella95, that few doctors know how best to treat patients who have hypothyroidism. It seems to me that they're told to only take the TSH and T4 into consideration, whilst the Active thyroid hormone is T3 and T4 is inactive (it has to convert to the Active T3). It is T3 that's needed by our T3 receptor cells.

shaws profile image
shawsAdministrator

Unless you are very frail with a heart disease, the starting dose is 50mcg of levo with a blood test every six weeks with an increase of 25mcg until TSH is 1 or lower.

All blood tests have to be at the very earliest, fasting (you can drink water) and allow a gap of 24 hours between last dose and test and take it afterwards. This helps keep the TSH at its highest as doctors seem to only pay attention to the TSH instead of Free T4 and Free T4 which should be nearer the upper part of the levels.

EllaRoulette profile image
EllaRoulette in reply to shaws

I do have a lot of chronic condition including a heart condition, so maybe they were trying to be cautious, I don't know. Ok thank you. Ok thank you for all the information :)

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